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用于材料和医学科学应用的基于实验室的X射线相衬成像技术。

Laboratory-based X-ray phase-contrast imaging technique for material and medical science applications.

作者信息

Kashyap Yogesh S, Yadav P S, Roy Tushar, Sarkar P S, Shukla M, Sinha Amar

机构信息

Laser and Neutron Physics Section, Bhabha Atomic Research Centre, Mumbai 400085, India.

出版信息

Appl Radiat Isot. 2008 Aug;66(8):1083-90. doi: 10.1016/j.apradiso.2007.12.008. Epub 2007 Dec 23.

DOI:10.1016/j.apradiso.2007.12.008
PMID:18313312
Abstract

In-line X-ray phase-contrast imaging technique is an emerging method for the study of materials such as carbon fibers, carbon composite materials, polymers, etc. Similarly this technique is also well suited for the imaging of soft materials such as tissues, distinguishing between tumor and normal tissue. These represent the class of materials for which X-ray attenuation cross-section is very small. Thus this method promises a far better contrast for low X-ray absorbing substances than the conventional radiography method. We have set up an experimental facility using a combination of X-ray CCD detector and a microfocus X-ray source. This facility is dedicated to micro-imaging experiments such as microtomography and high-resolution phase-contrast experiments. In this paper, the results of X-ray phase-contrast imaging experiments are described.

摘要

在线X射线相衬成像技术是一种用于研究碳纤维、碳复合材料、聚合物等材料的新兴方法。同样,该技术也非常适合对软组织进行成像,比如区分肿瘤组织和正常组织。这些材料的X射线衰减截面非常小。因此,与传统的放射成像方法相比,这种方法有望为低X射线吸收物质提供更好的对比度。我们利用X射线CCD探测器和微焦点X射线源组合搭建了一个实验装置。该装置专门用于微观成像实验,如显微断层扫描和高分辨率相衬实验。本文描述了X射线相衬成像实验的结果。

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引用本文的文献

1
Phase-contrast imaging with a compact x-ray light source: system design.紧凑型X射线光源的相衬成像:系统设计
J Med Imaging (Bellingham). 2017 Oct;4(4):043503. doi: 10.1117/1.JMI.4.4.043503. Epub 2017 Nov 23.
2
In Vitro Validation of an Artefact Suppression Algorithm in X-Ray Phase-Contrast Computed Tomography.X射线相衬计算机断层扫描中伪影抑制算法的体外验证
PLoS One. 2015 Aug 21;10(8):e0135654. doi: 10.1371/journal.pone.0135654. eCollection 2015.
3
Realistic wave-optics simulation of X-ray phase-contrast imaging at a human scale.
人体尺度下X射线相衬成像的真实波动光学模拟
Sci Rep. 2015 Jul 14;5:12011. doi: 10.1038/srep12011.
4
Feasibility testing of a pre-clinical coded aperture phase contrast imaging configuration using a simple fast Monte Carlo simulator.使用简单快速蒙特卡罗模拟器对临床前编码孔径相衬成像配置进行可行性测试。
Biomed Opt Express. 2013 Dec 4;5(1):93-105. doi: 10.1364/BOE.5.000093.