Soukup-Hein Renee J, Remsburg Jeffrey W, Breitbach Zachary S, Sharma Pritesh S, Payagala Tharanga, Wanigasekara Eranda, Huang Junmin, Armstrong Daniel W
Department of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, Texas 76019, USA.
Anal Chem. 2008 Apr 1;80(7):2612-6. doi: 10.1021/ac7023848. Epub 2008 Mar 4.
The analysis of anions remains an important task for many areas of science, and new sensitive analytical methods continue to be of great interest. In this study, we present the use of 17 tricationic reagents for use as gas-phase ion pairing agents for divalent anions. When the anion pairs with the tricationic reagent, an overall positive charge is retained and enables detection by ESI-MS in the positive mode. The 17 tricationic reagents were made from 1 of 4 core structures and 7 terminal charged groups. The effect of these structural elements on the detection sensitivity of the complex is examined empirically. A comparison of signal-to-noise ratios achieved in positive and negative modes also is presented.
阴离子分析在许多科学领域仍然是一项重要任务，新的灵敏分析方法一直备受关注。在本研究中，我们展示了17种三价阳离子试剂用作二价阴离子的气相离子配对剂。当阴离子与三价阳离子试剂配对时，整体正电荷得以保留，从而能够通过正模式电喷雾电离质谱（ESI-MS）进行检测。这17种三价阳离子试剂由4种核心结构之一和7种末端带电基团制成。通过实验研究了这些结构元素对络合物检测灵敏度的影响。还给出了在正模式和负模式下获得的信噪比的比较。
