Reid D B, Pollock J G
Unit for Peripheral Vascular Surgery, Glasgow Royal Infirmary, Scotland.
Ann Vasc Surg. 1991 Jul;5(4):320-4. doi: 10.1007/BF02015291.
A gelatin-sealed knitted Dacron graft has been developed which has zero porosity at implantation and does not require preclotting. Its patency rate up to 57 months and effectiveness at saving blood loss have been studied. Gelatin-sealed aortic grafts were implanted into 100 consecutive patients--77 men, 23 women. Surgery was performed for aneurysm in 36 patients (including four with rupture), intermittent claudication in 44, rest pain in 17, and gangrene in three, over an 18 month period. The patients were followed up prospectively for 57 months. Perioperative mortality was 1%. Cumulative primary graft patency was 99%. There was no measurable blood loss at implantation. Forty-seven patients required blood transfusion: mean volume transfused was 430 ml. There were no problems related to the sealant.
一种明胶密封的针织涤纶移植物已被研发出来，它在植入时孔隙率为零，且无需预凝。对其长达57个月的通畅率和减少失血的效果进行了研究。将明胶密封的主动脉移植物植入了连续100例患者体内——77名男性，23名女性。在18个月的时间里，36例患者因动脉瘤接受手术（包括4例破裂患者），44例因间歇性跛行，17例因静息痛，3例因坏疽。对患者进行了为期57个月的前瞻性随访。围手术期死亡率为1%。原发性移植物累计通畅率为99%。植入时无明显失血。47例患者需要输血：平均输血量为430毫升。未出现与密封剂相关的问题。
