Leahy T Ronan, Webb David W M, Hoey Hilary, Butler Karina M
Department of Paediatric Neurology, National Children's Hospital, Tallaght, Crumlin, Ireland.
Pediatr Infect Dis J. 2008 Apr;27(4):362-3. doi: 10.1097/INF.0b013e318160ee11.
Neurologic complications can occur with varicella-zoster virus (VZV) infection, usually after vesicular exanthem. We report the case of a previously healthy 14-year-old boy with aseptic meningitis as a result of reactivated-VZV infection without exanthem. Diagnosis was made by detection of VZV-DNA in cerebrospinal fluid. VZV should be considered in cases of aseptic meningitis, even without a history of exanthem or immune compromise.
神经系统并发症可发生于水痘带状疱疹病毒(VZV)感染后,通常在出现水疱性皮疹之后。我们报告一例既往健康的14岁男孩,因VZV再激活感染导致无菌性脑膜炎,且无皮疹表现。通过检测脑脊液中的VZV-DNA做出诊断。即使没有皮疹病史或免疫功能低下,无菌性脑膜炎病例也应考虑VZV感染。