Thordsen John E, Harris Lindsey, Hubbard G Baker
Retina Service, Emory Eye Center, Emory University School of Medicine, Atlanta, Georgia, USA.
Retina. 2008 Mar;28(3 Suppl):S3-7. doi: 10.1097/IAE.0b013e318159ec7f.
To report the etiology, culture results, management techniques, and visual outcomes for pediatric endophthalmitis at Emory University for the past 10 years.
Retrospective chart review based on a computer generated database of all cases of endophthalmitis occurring in patients younger than 18 years from 1995 to 2005.
Sixteen cases of pediatric endophthalmitis were identified. Ocular trauma and previous ocular surgery were the most common etiologies, accounting for 44% and 38% of cases respectively. Nine cases (56%) had positive vitreous cultures. Sixty-six percent of cases with positive vitreous cultures involved Gram-positive species. All patients were treated with intravitreal antibiotics. Primary vitrectomy was performed in nine cases. Subsequent to the intraocular infection, 6 eyes (38%) developed retinal detachments. At last follow-up, visual acuity of 20/400 or better was obtained in only 6 eyes (38%).
Pediatric endophthalmitis in this series most commonly resulted from penetrating ocular trauma or from ocular surgery. Retinal detachment commonly occurred as a complication. Despite aggressive management with antibiotics and in many cases vitrectomy, visual outcomes were poor in this series.
报告过去10年里埃默里大学小儿眼内炎的病因、培养结果、治疗方法及视力预后情况。
基于计算机生成的数据库,对1995年至2005年间18岁以下患者发生的所有眼内炎病例进行回顾性病历审查。
共确定16例小儿眼内炎病例。眼外伤和既往眼部手术是最常见的病因,分别占病例的44%和38%。9例(56%)玻璃体培养呈阳性。玻璃体培养阳性的病例中66%涉及革兰氏阳性菌。所有患者均接受了玻璃体腔内抗生素治疗。9例患者接受了一期玻璃体切除术。眼内感染后,6只眼(38%)发生了视网膜脱离。在最后一次随访时,仅6只眼(38%)的视力达到20/400或更好。
本系列小儿眼内炎最常见的病因是穿透性眼外伤或眼部手术。视网膜脱离是常见的并发症。尽管采用了积极的抗生素治疗且在许多病例中进行了玻璃体切除术,但本系列的视力预后较差。