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越南北方开放性眼球损伤后小儿眼内炎的临床和微生物学特征

Clinical and Microbiological Features of Pediatric Endopthalmitis After Open Globe Injury in the North of VietNam.

作者信息

Van Tham Truong Khanh, Hon Do Nhu, Anh Nguyen Thi Ngoc, Anh Bui Thị Van, Quyet Do, Thai Than Van, Nga Vu Thi, Bac Nguyen Duy

机构信息

Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.

Vienam Ophthalmology Society, Hanoi, Vietnam.

出版信息

Open Access Maced J Med Sci. 2019 Dec 20;7(24):4306-4310. doi: 10.3889/oamjms.2019.380. eCollection 2019 Dec 30.

Abstract

BACKGROUND

Pediatric endophthalmitis after open-globe injury had its clinical features, microbiological profile different from those in aldults. In Viet Nam, there was no report on the clinical and microbiological characteristics of pediatric posttraumatic endophthalmitis. Therefore, we conduct this study.

AIM

To describe clinical features, ultrasound results, gram stain and culture results of endophthalmitis in pediatric open globe injuries.

METHODS

Prospective non-controlled study. Case series of 30 eyes presenting with post-traumatic endophthalmitis between 2015 and 2016 were reviewed.

RESULTS

Mean age was 8.03 ± 3.99 years. Metallic and organic etiologies were the most common causes for injuries (n = 11). 27 cases had penetrating corneal trauma. Dense opaque vitreous was seen in 25 eyes. Retinal necrosis < 1 quadrant and chorioretinal abscess > 1 quadrant were the most common fundus lesions. Dense vitreous opacity on ultrasound was most common (n = 28). Gram stain bacteria positivity was 93.3%, gram-positive was isolated in 63.3%. Vitreous samples were more often positive than aqueous (P = 0,002).

CONCLUSION

Posttraumatic endophthalmitis in children is more common in boys aged 6-10 years and most often caused by injury with metallic and organic matters. Culture results were very low. Vitreous samples were more often positive than aqueous. Gram-positive bacteria were the most common causative organism.

摘要

背景

开放性眼球损伤后发生的小儿眼内炎,其临床特征和微生物学特征与成人不同。在越南,尚无关于小儿创伤后眼内炎临床和微生物学特征的报道。因此,我们开展了这项研究。

目的

描述小儿开放性眼球损伤所致眼内炎的临床特征、超声检查结果、革兰氏染色及培养结果。

方法

前瞻性非对照研究。回顾了2015年至2016年间30例创伤后眼内炎患儿的病例系列。

结果

平均年龄为8.03±3.99岁。金属和有机物致伤是最常见的原因(n = 11)。27例有穿透性角膜外伤。25只眼可见浓密的不透明玻璃体。视网膜坏死<1个象限和脉络膜视网膜脓肿>1个象限是最常见的眼底病变。超声检查显示浓密的玻璃体混浊最常见(n = 28)。革兰氏染色细菌阳性率为93.3%,分离出革兰氏阳性菌的比例为63.3%。玻璃体样本的阳性率高于房水样本(P = 0.002)。

结论

儿童创伤后眼内炎在6 - 10岁男孩中更为常见,最常见的原因是金属和有机物损伤。培养结果很低。玻璃体样本的阳性率高于房水样本。革兰氏阳性菌是最常见的致病菌。

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本文引用的文献

1
Pediatric open-globe injury in a university-based tertiary hospital.一所大学附属三级医院中的儿童开放性眼球损伤
Eur J Ophthalmol. 2020 Mar;30(2):269-274. doi: 10.1177/1120672118818013. Epub 2018 Dec 12.
3
Pediatric Posttraumatic Endophthalmitis in China for Twenty Years.中国儿童创伤后眼内炎二十年回顾
J Ophthalmol. 2017;2017:5248767. doi: 10.1155/2017/5248767. Epub 2017 Jan 16.
6
Epidemiological Features of Pediatric Ocular Trauma in Egypt.埃及儿童眼外伤的流行病学特征
J Ophthalmol. 2016;2016:7874084. doi: 10.1155/2016/7874084. Epub 2016 Oct 5.
7
Pediatric posttraumatic endophthalmitis.小儿创伤性眼内炎
Graefes Arch Clin Exp Ophthalmol. 2016 Oct;254(10):1919-1922. doi: 10.1007/s00417-016-3330-1. Epub 2016 Apr 12.
10
A multicentre prospective study of post-traumatic endophthalmitis.多中心前瞻性外伤性眼内炎研究。
Acta Ophthalmol. 2013 Aug;91(5):475-82. doi: 10.1111/j.1755-3768.2011.02349.x. Epub 2012 Feb 7.

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