Abel R, Keil M, Schläger E, Akbar M
Orthopädische Universitätsklinik Heidelberg, Germany.
Spinal Cord. 2008 Sep;46(9):595-602. doi: 10.1038/sc.2008.11. Epub 2008 Mar 4.
Retrospective study utilizing the standard patient data documentation of a spinal cord injury (SCI) unit.
To examine the efficacy and outcome of posterior decompression and stabilization for metastatic cord compression.
Orthopedic university hospital with large SCI unit.
The 34 consecutive patients who had presented with symptoms of spinal cord compression due to metastatic disease and progressive neurologic deficit were treated using a uniform surgical approach (posterior decompression and stabilization). After surgery, all treatment options available in a full-featured SCI unit were applied as necessary and suitable. Outcome was rated concerning neurologic function (American Spinal Injury Association, ASIA), functional status (Functional Independence Measure) and pain. The results were compared to the published results, focusing on publications describing results of anterior surgical approaches to the spine.
Evaluation of the results of the ASIA exams showed that progression of the neurologic deficit could be stopped in the majority of cases-however recovery of neurologic function was rare. The functional status could be improved markedly and good pain reduction was achieved.
I mmediate surgery can be recommended if the general condition of the patient warrants surgical intervention. Using accepted standards of documentation for SCI, a clear perspective of the results that can be expected is provided. Comparing the results of this study with the current literature there is no evidence that anterior approaches are superior.
利用脊髓损伤(SCI)科室的标准患者数据记录进行回顾性研究。
探讨后路减压与固定术治疗转移性脊髓压迫症的疗效及结果。
设有大型SCI科室的骨科大学医院。
对34例因转移性疾病出现脊髓压迫症状且伴有进行性神经功能缺损的连续患者采用统一的手术方法(后路减压与固定术)进行治疗。术后,根据需要和适宜情况应用了功能齐全的SCI科室提供的所有治疗方案。对神经功能(美国脊髓损伤协会,ASIA)、功能状态(功能独立性测量)和疼痛方面的结果进行了评定。将结果与已发表的结果进行比较,重点关注描述脊柱前路手术结果的文献。
对ASIA检查结果的评估显示,在大多数病例中神经功能缺损的进展可以停止——然而神经功能恢复很少见。功能状态可得到显著改善,疼痛也能明显减轻。
如果患者的一般状况允许手术干预,可建议立即手术。采用SCI公认的记录标准,能清晰地了解预期的结果。将本研究结果与当前文献进行比较,没有证据表明前路手术更具优势。