Mittal Khush, Soslow Robert, McCluggage W G
Department of Pathology, NYU School of Medicine and Surgical and Ob-Gyn Pathology, Bellevue Hospital, Room 4 west 1, 462 First Ave, New York, NY 10016, USA.
Arch Pathol Lab Med. 2008 Mar;132(3):402-23. doi: 10.5858/2008-132-402-AOITGP.
A large variety of tumors and lesions arise in the female genital tract. Although the majority of these can be correctly recognized on routine hematoxylin-eosin-stained slides, occasional cases present a diagnostic challenge. Immunohistochemical stains are extremely useful in resolving many of these problematic cases. As the knowledge in this area is constantly expanding, it is useful to have this updated information in a review form for easy access.
To present our current knowledge of immunohistochemistry of the lesions of the female genital tract in a readily accessible form.
The review is based on previously published articles on this topic.
Immunohistochemical stains help in reaching a conclusive diagnosis in a variety of problematic lesions seen in gynecologic pathology. As in any other system, immunohistochemical findings need to be interpreted in light of the clinical history and morphologic findings.
女性生殖道会出现各种各样的肿瘤和病变。尽管其中大多数在常规苏木精-伊红染色切片上能够得到正确识别，但偶尔也会出现诊断难题。免疫组织化学染色在解决许多此类疑难病例中极为有用。由于该领域的知识在不断扩展，以综述形式提供这些最新信息以便于查阅是很有必要的。
以易于获取的形式呈现我们目前对女性生殖道病变免疫组织化学的认识。
本综述基于此前发表的关于该主题的文章。
免疫组织化学染色有助于对妇科病理学中所见的各种疑难病变做出确定性诊断。与其他任何系统一样，免疫组织化学结果需要结合临床病史和形态学表现进行解读。
