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本文引用的文献

1
The role of DOTS in tuberculosis treatment and control.直接督导下的短程化疗在结核病治疗与控制中的作用。
Am J Respir Med. 2003;2(3):203-9. doi: 10.1007/BF03256649.
2
Is the DOTS strategy sufficient to achieve tuberculosis control in low- and middle-income countries? 1. Need for interventions in universities and medical schools.直接观察短程治疗(DOTS)策略是否足以在低收入和中等收入国家实现结核病控制?1. 需要对大学和医学院采取干预措施。
Int J Tuberc Lung Dis. 2003 Jun;7(6):509-15.

波斯尼亚和黑塞哥维那实施直接督导下的短程化疗超过十年。

More than ten years of DOTS in Bosnia and Herzegovina.

作者信息

Zutić Hasan, Dizdarević Zehra, Ustamujić Aida, Hadzimurtezić Zlatan

机构信息

Clinic for Lung Disease and Tuberculosis Podhrastovi, University of Sarajevo Clinics Centre, Bardakcije 90, 71 000 Sarajevo, Bosnia and Herzegovina.

出版信息

Bosn J Basic Med Sci. 2008 Feb;8(1):52-7. doi: 10.17305/bjbms.2008.2998.

DOI:10.17305/bjbms.2008.2998
PMID:18318673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5724877/
Abstract

Directly Observed Therapy Short-course (DOTS) is composed of five distinct elements: political commitment, case detection through quality-assured bacteriology; drug supplies; surveillance and monitoring systems and use of highly efficacious regimens; and direct observation of treatment. DOTS produces cure rates of up to 95 percent even in the poorest countries and prevents the development of Multi-Drug Resistant Tuberculosis. National TB Programme (NTP) has been started to introduce in 1994 according to DOTS principles in B&H with central and regional levels. At central levels there are national TB coordinators, and in all Cantons/Regions there are regional TB Coordinators. During intensive phase of therapy, patients are hospitalized. In the second phase of therapy, patients are treated in anti-tuberculosis dispensaries and some of them by a responsible member of the family (family supervision). There are several weaknesses in implementation of DOTS in B&H: TB case detection was not fully implemented in all medical services. Registration of TB cases in some facilities, there is no official central recommended registry, individual reporting for treatment outcomes and establishing a reliable monitoring and evaluation system. Application for 6 round of The Global Fund to Fight AIDS, TB and Malaria (GFATM) had been finally approved and signed for B&H in October 2007. These grants would repair some implementation gaps and improve DOTS strategy in B&H.

摘要

直接观察治疗短程疗法(DOTS)由五个不同要素组成:政治承诺;通过质量有保证的细菌学进行病例发现;药品供应;监测和监督系统以及使用高效治疗方案;以及治疗的直接观察。即使在最贫穷的国家,DOTS也能产生高达95%的治愈率,并防止耐多药结核病的发展。波斯尼亚和黑塞哥维那(简称“波黑”)于1994年开始根据DOTS原则在中央和地区层面启动国家结核病防治规划(NTP)。在中央层面设有国家结核病协调员,在所有县/地区设有地区结核病协调员。在治疗强化阶段,患者住院治疗。在治疗的第二阶段,患者在抗结核诊疗所接受治疗,其中一些患者由家庭成员负责监督(家庭督导)。波黑在实施DOTS方面存在一些弱点:并非所有医疗服务机构都全面实施了结核病病例发现工作。在一些机构中,结核病病例登记没有官方中央推荐的登记册,缺乏关于治疗结果的个人报告以及建立可靠的监测和评估系统。2007年10月,波黑最终获批并签署了第六轮全球抗击艾滋病、结核病和疟疾基金(GFATM)的申请。这些赠款将弥补一些实施方面的差距,并改善波黑的DOTS战略。