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黑曲霉1a型线粒体DNA与管囊曲霉2b型线粒体DNA完整基因组的比较分析。

Comparative analysis of the complete mitochondrial genomes of Aspergillus niger mtDNA type 1a and Aspergillus tubingensis mtDNA type 2b.

作者信息

Juhász Akos, Pfeiffer Ilona, Keszthelyi Andrea, Kucsera Judit, Vágvölgyi Csaba, Hamari Zsuzsanna

机构信息

Department of Microbiology, Faculty of Sciences, University of Szeged, Szeged, Hungary.

出版信息

FEMS Microbiol Lett. 2008 Apr;281(1):51-7. doi: 10.1111/j.1574-6968.2008.01077.x.

Abstract

To understand the differences in the organization of mitochondrial genomes of the very closely related Aspergillus niger and Aspergillus tubingensis species, we determined the complete genome sequence of the 1a mtDNA type of A. niger and 2b mtDNA type of A. tubingensis and now we provide a comparative analysis of the two mtDNAs. We found that (1) the organization (gene content and order) of the two genomes is almost identical and (2) the size difference between them is principally attributed to the different intron content of their cox1, atp9 and ndh4L genes.

摘要

为了解密切相关的黑曲霉和管囊曲霉物种线粒体基因组组织的差异,我们测定了黑曲霉1a型线粒体DNA(mtDNA)和管囊曲霉2b型mtDNA的完整基因组序列,现在我们对这两种mtDNA进行了比较分析。我们发现:(1)两个基因组的组织(基因含量和顺序)几乎相同;(2)它们之间的大小差异主要归因于其细胞色素氧化酶亚基1(cox1)、ATP合酶亚基9(atp9)和NADH脱氢酶亚基4L(ndh4L)基因内含子含量的不同。

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