Romano R, Losi M A, Migliore T, Contaldi C, Parrella L S, Caputi A, Betocchi S
Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University Federico II School of Medicine, Naples, Italy.
Minerva Cardioangiol. 2008 Apr;56(2):181-7.
The aim of this study was to assess the relationship between echocardiographic indexes of left ventricular (LV) hypertrophy with LV mass (LVM) obtained at cardiac magnetic resonance (CMR) in a population of patients with hypertrophic cardiomiopathy (HCM).
Thirty-nine patients with HCM underwent echocardiography and CMR. By echocardiography maximal wall thickness (MWT), Spirito' and Maron's hypertrophy index and the Wigle's score were obtained. Absolute LVM was measured through CMR and indexed to body surface area (LVMi). Data were analysed using linear regression analysis.
In 31% of patients there was an incomplete echocardiographic LV anatomic characterization. However, there was a good correlation between MWT measured at echocardiography and at CMR (P<0.001; r=0.755). Overall echocardiographic indexes of LV hypertrophy correlate with either LVM and LVMi: MWT (P=0.008, r=0.420 and P=0.003, r=0.467, respectively); Spirito' and Maron's hypertrophy index (P=0.003, r=0.551 and P=0.001, r=0.606, respectively) and Wigle's score (P=0.004, r=0.522 and P=0.004, r=0.522, respectively).
In our HCM population, although a complete anatomic LV anatomic characterization was not obtained by echocardiography in all patients, echocardiographic hypertrophic indexes showed a good correlation with LVM obtained by CMR.
本研究旨在评估肥厚型心肌病（HCM）患者群体中，经胸超声心动图测定的左心室（LV）肥厚的超声心动图指标与心脏磁共振成像（CMR）获得的左心室质量（LVM）之间的关系。
39例HCM患者接受了超声心动图和CMR检查。通过超声心动图获得最大壁厚度（MWT）、斯皮里托和马龙肥厚指数以及威格勒评分。通过CMR测量绝对LVM，并将其与体表面积（LVMi）进行指数化。使用线性回归分析对数据进行分析。
31%的患者存在超声心动图对左心室解剖特征的不完全描述。然而，超声心动图测量的MWT与CMR测量的MWT之间存在良好的相关性（P<0.001；r=0.755）。总体而言，左心室肥厚的超声心动图指标与LVM和LVMi均相关：MWT（分别为P=0.008，r=0.420和P=0.003，r=0.467）；斯皮里托和马龙肥厚指数（分别为P=0.003，r=0.551和P=0.001，r=0.606）以及威格勒评分（分别为P=0.004，r=0.522和P=0.004，r=0.522）。
在我们的HCM患者群体中，尽管并非所有患者都能通过超声心动图获得完整的左心室解剖特征描述，但超声心动图肥厚指标与CMR获得的LVM显示出良好的相关性。
