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The management of plasma glucose in acute cerebral ischaemia and traumatic brain injury: more research needed.

作者信息

Strong Anthony J

出版信息

Intensive Care Med. 2008 Jul;34(7):1169-72. doi: 10.1007/s00134-008-1045-4. Epub 2008 Mar 5.

DOI:10.1007/s00134-008-1045-4
PMID:18320166
Abstract
摘要

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The management of plasma glucose in acute cerebral ischaemia and traumatic brain injury: more research needed.急性脑缺血和创伤性脑损伤中血糖的管理：仍需更多研究。
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Glucose control in acute brain injury: does it matter?急性脑损伤中的血糖控制：有关系吗？
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Glycemic control after brain injury: boon and bane for the brain.脑损伤后的血糖控制：对大脑的利弊
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Pro: Tight control of blood glucose in the brain-injured patient is important and desirable.赞成观点：对脑损伤患者进行严格的血糖控制很重要且值得追求。
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Increased glucose availability does not restore prolonged spreading depression durations in hypotensive rats without brain injury.葡萄糖供应增加并不能恢复无脑损伤低血压大鼠延长的扩散性抑制持续时间。
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Treating hyperglycemia in neurocritical patients: benefits and perils.神经危重症患者的高血糖治疗：获益与风险。
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Spreading depolarizations cycle around and enlarge focal ischaemic brain lesions.

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Spreading depolarizations occur in human ischemic stroke with high incidence.去极化扩散在人类缺血性中风中发生率很高。
Ann Neurol. 2008 Jun;63(6):720-8. doi: 10.1002/ana.21390.
2
Hyperglycemia and cerebral glucose in aneurysmal subarachnoid hemorrhage.动脉瘤性蛛网膜下腔出血中的高血糖与脑葡萄糖
Intensive Care Med. 2008 Jul;34(7):1200-7. doi: 10.1007/s00134-008-1044-5. Epub 2008 Mar 5.
3
Glucose control after severe brain injury.重度脑损伤后的血糖控制。
扩布性去极化在局灶性缺血性脑损伤周围循环和扩大。
Brain. 2010 Jul;133(Pt 7):1994-2006. doi: 10.1093/brain/awq117. Epub 2010 May 26.
4
A review of perioperative glucose control in the neurosurgical population.神经外科患者围手术期血糖控制的综述。
J Diabetes Sci Technol. 2009 Nov 1;3(6):1352-64. doi: 10.1177/193229680900300615.
5
Systemic glucose and brain energy metabolism after subarachnoid hemorrhage.蛛网膜下腔出血后系统葡萄糖和脑能量代谢。
Neurocrit Care. 2010 Jun;12(3):317-23. doi: 10.1007/s12028-009-9327-4.
6
Bleeding in the brain: Killer waves of depolarization in subarachnoid bleed.脑内出血：蛛网膜下腔出血中的去极化致死波。
Nat Med. 2009 Oct;15(10):1131-2. doi: 10.1038/nm1009-1131.
7
Optimizing cerebral glucose in severe traumatic brain injury: still some way to go.优化重度创伤性脑损伤患者的脑葡萄糖代谢：仍有很长的路要走。
Crit Care. 2009;13(2):131. doi: 10.1186/cc7753. Epub 2009 Apr 6.
8
Year in review in Intensive Care Medicine, 2008: I. Brain injury and neurology, renal failure and endocrinology, metabolism and nutrition, sepsis, infections and pneumonia.《2008年重症医学年度回顾：I. 脑损伤与神经病学、肾衰竭与内分泌学、代谢与营养、脓毒症、感染与肺炎》
Intensive Care Med. 2009 Jan;35(1):30-44. doi: 10.1007/s00134-008-1371-6. Epub 2008 Dec 9.
Curr Opin Clin Nutr Metab Care. 2008 Mar;11(2):134-9. doi: 10.1097/MCO.0b013e3282f37b43.
4
Peri-infarct depolarizations lead to loss of perfusion in ischaemic gyrencephalic cerebral cortex.梗死灶周围去极化导致缺血性脑回状大脑皮质灌注丧失。
Brain. 2007 Apr;130(Pt 4):995-1008. doi: 10.1093/brain/awl392.
5
Glucose-potassium-insulin infusions in the management of post-stroke hyperglycaemia: the UK Glucose Insulin in Stroke Trial (GIST-UK).葡萄糖-钾-胰岛素输注治疗卒中后高血糖：英国卒中葡萄糖胰岛素试验（GIST-UK）
Lancet Neurol. 2007 May;6(5):397-406. doi: 10.1016/S1474-4422(07)70080-7.
6
Glucose and the ischaemic brain: too much of a good thing?葡萄糖与缺血性脑：有益之物是否过量？
Lancet Neurol. 2007 May;6(5):380-1. doi: 10.1016/S1474-4422(07)70086-8.
7
Delayed ischaemic neurological deficits after subarachnoid haemorrhage are associated with clusters of spreading depolarizations.蛛网膜下腔出血后迟发性缺血性神经功能缺损与去极化扩散波群有关。
Brain. 2006 Dec;129(Pt 12):3224-37. doi: 10.1093/brain/awl297. Epub 2006 Oct 25.
8
Vasoconstrictive neurovascular coupling during focal ischemic depolarizations.局灶性缺血性去极化期间的血管收缩性神经血管耦合
J Cereb Blood Flow Metab. 2006 Aug;26(8):1018-30. doi: 10.1038/sj.jcbfm.9600252. Epub 2005 Dec 7.
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Hyperglycemia, insulin, and acute ischemic stroke: a mechanistic justification for a trial of insulin infusion therapy.高血糖、胰岛素与急性缺血性卒中：胰岛素输注治疗试验的机制依据
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Insulin therapy protects the central and peripheral nervous system of intensive care patients.胰岛素治疗可保护重症监护患者的中枢和周围神经系统。
Neurology. 2005 Apr 26;64(8):1348-53. doi: 10.1212/01.WNL.0000158442.08857.FC.