Srivastava Sudhanshu, Ball Vincent, Podsiadlo Paul, Lee Jungwoo, Ho Peter, Kotov Nicholas A
Departments of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.
J Am Chem Soc. 2008 Mar 26;130(12):3748-9. doi: 10.1021/ja7110288. Epub 2008 Mar 6.
The exponentially growing layer-by-layer (LBL) films made from poly(diallyldimethylammonium chloride) (PDDA) and poly(acrylic acid) (PAA) were used to load and unload the CdTe nanoparticles (NPs). The reversible loading of NPs were investigated through UV-vis studies and further confirmed by confocal microscopy. In addition the LBL films were also compared for the release kinetics for pH 9 and 7 and films capped with (PDDA-PSS)10 layers. The amount of released particles at pH 9 was found to be at least 2 orders of magnitude higher than those at pH 7 and with (PDDA-PSS)10 capped layers after 25 h. This variation in film response for CdTe-particle release presents a route for studies in which highly swollen exponentially growing LBL films can be loaded with functionalized NPs for biological applications and explored as carriers to hold the NPs inside the films for self-assembly.
由聚二烯丙基二甲基氯化铵（PDDA）和聚丙烯酸（PAA）制成的指数生长层层（LBL）膜用于装载和卸载碲化镉纳米颗粒（NPs）。通过紫外可见光谱研究对NPs的可逆装载进行了研究，并通过共聚焦显微镜进一步证实。此外，还比较了LBL膜在pH值为9和7时的释放动力学，以及用（PDDA-PSS）10层封端的膜。发现在25小时后，pH值为9时释放的颗粒数量比pH值为7时以及用（PDDA-PSS）10层封端的膜至少高2个数量级。CdTe颗粒释放的膜响应变化为研究提供了一条途径，即高度溶胀的指数生长LBL膜可以装载功能化的NPs用于生物应用，并作为载体将NPs保持在膜内用于自组装。
