Kim Seung Kab, Cho Byung Joo, Hong Samin, Kang Sung Yong, Kim Jae Sung, Kim Chan Yun, Seong Gong Je
Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
Korean J Ophthalmol. 2008 Mar;22(1):6-9. doi: 10.3341/kjo.2008.22.1.6.
To determine the normal reference range of pulsatile ocular blood flow (POBF) values in healthy Korean subjects and to find out the factors that may affect them.
A total of 280 eyes of 280 normal subjects were included in this study. Best corrected visual acuity (BCVA), intraocular pressure (IOP), axial length, POBF, systemic blood pressure, and pulse rate were measured. The mean, standard deviation, range, and the 5th and 95th percentiles of POBF were calculated, and the influences of various parameters to POBF were determined by multiple regression analyses.
The mean POBF value was 766.0+/-221.6 microl/min in men and 1021.1+/-249.5 microl/min in women. The 5th and 95th percentiles for POBF values were 486.0 microl/min and 1140.0 microl/min in men and 672.0 microl/min and 1458.0 microl/min in women. The POBF values were significantly influenced by gender, mean blood pressure, pulse rate, and axial length.
Even though the POBF values were influenced by gender, BP, and axial length, we could define the normal reference range of POBF in healthy Koreans.
确定健康韩国受试者搏动性眼血流（POBF）值的正常参考范围，并找出可能影响这些值的因素。
本研究纳入了280名正常受试者的280只眼。测量了最佳矫正视力（BCVA）、眼压（IOP）、眼轴长度、POBF、全身血压和脉搏率。计算了POBF的平均值、标准差、范围以及第5和第95百分位数，并通过多元回归分析确定了各种参数对POBF的影响。
男性的平均POBF值为766.0±221.6微升/分钟，女性为1021.1±249.5微升/分钟。男性POBF值的第5和第95百分位数分别为486.0微升/分钟和1140.0微升/分钟，女性为672.0微升/分钟和1458.0微升/分钟。POBF值受性别、平均血压、脉搏率和眼轴长度的显著影响。
尽管POBF值受性别、血压和眼轴长度的影响，但我们可以确定健康韩国人POBF的正常参考范围。
