食酸丛毛单胞菌性角膜炎在免疫功能低下角膜中的延迟发病及治疗反应经验
Experience of Comamonas acidovorans keratitis with delayed onset and treatment response in immunocompromised cornea.
作者信息
Lee Sang Mok, Kim Mee Kum, Lee Jae Lim, Wee Won Ryang, Lee Jin Hak
机构信息
Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
出版信息
Korean J Ophthalmol. 2008 Mar;22(1):49-52. doi: 10.3341/kjo.2008.22.1.49.
PURPOSE
To report 2 cases of Comamonas acidovorans keratitis in immunocompromised cornea.
METHODS
A complete review of the medical records of the two cases of Comamonas acidovorans keratitis.
RESULTS
We found some similarities in clinical courses of two cases. Both of them showed development of keratitis during the management with corticosteroids, delayed onset, slow response to antibiotics, and relatively less affected corneal epithelium.
CONCLUSIONS
Comamonas acidovorans is known as a less virulent organism. However it can cause an indolent infection that responds slowly even to adequate antibiotics therapy in immunocompromised corneas.
目的
报告2例免疫功能低下角膜感染食酸丛毛单胞菌性角膜炎的病例。
方法
对2例食酸丛毛单胞菌性角膜炎病例的病历进行全面回顾。
结果
我们发现这2例病例的临床病程存在一些相似之处。二者均在使用皮质类固醇治疗期间发生角膜炎，起病延迟，对抗生素反应缓慢，且角膜上皮受累相对较轻。
结论
食酸丛毛单胞菌是一种毒力较低的微生物。然而，在免疫功能低下的角膜中，它可引起一种隐匿性感染，即使采用充分的抗生素治疗，反应也较慢。
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