Song Yoo Mi, Shin Sun Young
Department of Ophthalmology, Hanyang University College of Medicine, Seoul, Korea.
Korean J Ophthalmol. 2008 Mar;22(1):66-9. doi: 10.3341/kjo.2008.22.1.66.
To report a case of bilateral ophthalmic artery occlusion in rhino-orbito-cerebral mucormycosis.
Reviewed clinical charts, photographs, and fluorescein angiography
An 89-year-old man with poorly controlled diabetes developed sudden bilateral ptosis, complete ophthalmoplegia of the right eye, and superior rectus palsy of the left eye. Brain and orbit magnetic resonance imaging showed midbrain infarction and mild diffuse sinusitis. On the 2nd day of hospitalization, sudden visual loss and light reflex loss developed. There were retinal whitening, absence of retinal arterial filling, and a total lack of choroidal perfusion on fluorescein angiography of the right eye. The left eye showed a cherry red spot in the retina and the absence of retinal arterial filling and partial choroidal perfusion on fluorescein angiography. On rhinologic examination, mucormyosis was noticed. Despite treatment, visual acuity and light reflex did not recover and he died 4 days after admission.
Bilateral ophthalmic artery occlusion can occur in rhino-orbital-cerebral mucormycosis.
报告1例鼻眶脑型毛霉菌病伴双侧眼动脉闭塞的病例。
回顾临床病历、照片及荧光素血管造影检查结果。
1名89岁糖尿病控制不佳的男性突然出现双侧上睑下垂、右眼完全性眼肌麻痹及左眼上直肌麻痹。脑和眼眶磁共振成像显示中脑梗死及轻度弥漫性鼻窦炎。住院第2天,突然出现视力丧失及光反射消失。右眼荧光素血管造影显示视网膜变白、视网膜动脉充盈缺失及脉络膜灌注完全缺失。左眼荧光素血管造影显示视网膜樱桃红斑、视网膜动脉充盈缺失及脉络膜部分灌注缺失。经鼻科检查发现毛霉菌病。尽管进行了治疗,但视力和光反射未恢复,患者入院4天后死亡。
鼻眶脑型毛霉菌病可发生双侧眼动脉闭塞。