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面神经麻痹是冠状病毒病相关鼻脑毛霉菌病流行期间的常见表现。

Facial Nerve Palsy as a Common Presentation during the Epidemic of Coronavirus Disease Associated Rhinocerebral Mucormycosis.

作者信息

Reddy Y Mounika, Goddanti Nitya, Kumar Kiran, Suresh Aparna, Muderla Rajesh, Shankar T, Gupta Manish, Sreenivas K, Darbha Subramanyam

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Govt. ENT Hospital, Osmania Medical College, Hyderabad, 500095 India.

Department of Otorhinolaryngology, Head and Neck Surgery, Govt. Medical College, Suryapet, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):3313-3320. doi: 10.1007/s12070-022-03143-9. Epub 2022 Sep 4.

Abstract

PURPOSE

The main purpose of this study is to highlight the involvement of the facial nerve as one of the presenting symptoms in patients suspected of coronavirus disease associated mucormycosis (CAM).

METHODS

This is a retrospective observational study conducted at a tertiary care referral centre which included 300 patients with past history of being treated for coronavirus disease and who presented to our department with symptoms of invasive fungal sinusitis. All the patients were evaluated clinically and radiologically for presence of facial nerve palsy (FNP) in suspected cases of CAM. All the patients were managed with combined modality treatment with antifungal therapy and radical endoscopic debridement of the necrotic tissue and fungal debris.

RESULTS

The data were analysed to assess the possible epidemiological factors linked to CAM. Diabetes mellitus was the most common associated factor identified for aggravating of CAM. FNP is also one of the common presentation seen among 53 patients with CAM.

CONCLUSION

FNP is an unusual but significant sign in presentation of mucormycosis. It could be easily misdiagnosed as cerebrovascular accident leading to delay in the treatment. During this era of Covid-19 pandemic where wearing of masks has become mandatory, there is a high probability of this finding to be missed. Thus, our study emphasises for thorough cranial nerve examination in all cases of CAM, for an early and an immediate intervention to prevent the spread of the disease and also to improve the overall general condition of the patient.

摘要

目的

本研究的主要目的是强调面神经受累是疑似冠状病毒病相关毛霉菌病(CAM)患者的主要症状之一。

方法

这是一项在三级医疗转诊中心进行的回顾性观察研究,纳入了300例有冠状病毒病治疗史且因侵袭性真菌性鼻窦炎症状前来我科就诊的患者。对所有疑似CAM病例的患者进行临床和影像学评估,以确定是否存在面神经麻痹(FNP)。所有患者均采用抗真菌治疗联合坏死组织和真菌碎片的根治性内镜清创术进行综合治疗。

结果

对数据进行分析,以评估与CAM相关的可能流行病学因素。糖尿病是已确定的加重CAM的最常见相关因素。FNP也是53例CAM患者中常见的表现之一。

结论

FNP是毛霉菌病表现中一种不常见但重要的体征。它很容易被误诊为脑血管意外,从而导致治疗延误。在新冠疫情这个口罩成为必需品的时代,这一发现很有可能被遗漏。因此,我们的研究强调对所有CAM病例进行全面的颅神经检查,以便早期立即干预,防止疾病传播并改善患者的整体状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f5/9702394/4036e2a6c368/12070_2022_3143_Fig1_HTML.jpg

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