Choi Jeong Sil
Department of Nursing Science, Konyang University, Seo-gu, Daejeon, Korea.
Taehan Kanho Hakhoe Chi. 2008 Feb;38(1):39-44. doi: 10.4040/jkan.2008.38.1.39.
The purpose of this study was to compare 1% chlorhexidine-gluconate/61% ethanol (CHG/Ethanol) emollient and 7.5% povidone-iodine (PVI) scrub for antimicrobial,residual effect, and skin condition.
CHG/Ethanol emollient hand hygiene was performed waterless, and brushless by operating doctors and nurses (N=20). PVI hand washing was performed with water and a brush (N=20) for 5 min. The subjects were asked to press their left hand in hand-shaped agar before a surgical scrub, immediately after a surgical scrub and after the operation. The amount of isolated microorganisms were calculated by counting the number of divided areas(1 x 1 cm, 160 cell) which were culture positive in the hand culture plate. The skin condition was evaluated.
The antimicrobial count of CHG/Ethanol emollient and PVI immediately post surgical scrub was 0.0 vs. 4.1 (p>.05), and after the operation was 0.1 vs. 37.8 (p>.05)respectively. The Residual effect of CHG/Ethanol emollient immediately post surgical scrub and after the operation were 0.0 vs. 0.1 (p>.05), and PVI were 4.1 vs. 37.8 (p>.05)respectively. The skin condition and satisfaction of CHG/Ethanol emollient was higher than PVI (p<.05).
The antimicrobial effect between CHG/Ethanol emollient and PVI were the same. Considering skin condition, satisfaction and allergic reaction CHG/Ethanol emollient for surgical scrub is recommended in Korea.
本研究旨在比较1%葡萄糖酸氯己定/61%乙醇（CHG/乙醇）润肤剂和7.5%聚维酮碘（PVI）擦洗剂在抗菌、残留效果及皮肤状况方面的差异。
由20名手术医生和护士采用无水、无刷方式使用CHG/乙醇润肤剂进行手部卫生清洁。20名人员采用用水和刷子的方式进行PVI洗手，持续5分钟。要求受试者在手术擦洗前、手术擦洗后即刻以及手术后将左手按压在手部形状的琼脂上。通过计算手部培养平板上培养呈阳性的分隔区域（1×1厘米，160个细胞）数量来计算分离出的微生物数量。对皮肤状况进行评估。
手术擦洗后即刻，CHG/乙醇润肤剂和PVI的抗菌计数分别为0.0和4.1（p>0.05），手术后分别为0.1和37.8（p>0.05）。手术擦洗后即刻及手术后，CHG/乙醇润肤剂的残留效果分别为0.0和0.1（p>0.05），PVI分别为4.1和37.8（p>0.05）。CHG/乙醇润肤剂的皮肤状况及满意度高于PVI（p<0.05）。
CHG/乙醇润肤剂和PVI的抗菌效果相同。考虑到皮肤状况、满意度及过敏反应，在韩国推荐使用CHG/乙醇润肤剂进行手术擦洗。
