Pakalniskiene J, Falkenhorst G, Lisby M, Madsen S B, Olsen K E P, Nielsen E M, Mygh A, Boel J, Mølbak K
Department of Epidemiology, Statens Serum Institut, Copenhagen, Denmark.
Epidemiol Infect. 2009 Mar;137(3):396-401. doi: 10.1017/S0950268808000484. Epub 2009 Feb 9.
In industrialized countries enterotoxigenic Escherichia coli (ETEC) is mainly diagnosed as a cause of travellers' diarrhoea, but it is also known to cause foodborne outbreaks. We report an outbreak of acute gastroenteritis caused by ETEC serotypes O92:H- and O153:H2 as well as Salmonella Anatum, which affected around 200 students and teachers after a high-school dinner in Greater Copenhagen, Denmark, November 2006. A retrospective cohort study showed that consumption of pasta salad with pesto was associated with an increased risk of illness (attack rate 59.4%; risk ratio 2.6, 95% confidence interval 1.2-5.7). Imported fresh basil used for preparation of the pesto was the most likely source of contamination. Although ETEC is associated with travellers' diarrhoea in Denmark, this outbreak suggests that a proportion of sporadic ETEC infections might be caused by contaminated imported foodstuffs. To improve food safety further, it is important to target this poorly regulated and researched area.
在工业化国家，产肠毒素大肠杆菌（ETEC）主要被诊断为旅行者腹泻的病因，但它也会引发食源性疾病暴发。我们报告了一起由ETEC血清型O92:H-和O153:H2以及鸭沙门氏菌引起的急性胃肠炎暴发事件，该事件于2006年11月在丹麦大哥本哈根的一次高中晚餐后影响了约200名学生和教师。一项回顾性队列研究表明，食用配有香蒜酱的意大利面沙拉会增加患病风险（发病率59.4%；风险比2.6，95%置信区间1.2 - 5.7）。用于制作香蒜酱的进口新鲜罗勒叶很可能是污染源。尽管在丹麦ETEC与旅行者腹泻有关，但此次暴发表明，一部分散发性ETEC感染可能是由受污染的进口食品引起的。为了进一步提高食品安全，针对这个监管不力且研究较少的领域很重要。
