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2006年11月在丹麦一场高中晚宴后发生的产肠毒素大肠杆菌和鸭沙门氏菌感染的食源性疾病暴发。

A foodborne outbreak of enterotoxigenic E. coli and Salmonella Anatum infection after a high-school dinner in Denmark, November 2006.

作者信息

Pakalniskiene J, Falkenhorst G, Lisby M, Madsen S B, Olsen K E P, Nielsen E M, Mygh A, Boel J, Mølbak K

机构信息

Department of Epidemiology, Statens Serum Institut, Copenhagen, Denmark.

出版信息

Epidemiol Infect. 2009 Mar;137(3):396-401. doi: 10.1017/S0950268808000484. Epub 2009 Feb 9.

Abstract

In industrialized countries enterotoxigenic Escherichia coli (ETEC) is mainly diagnosed as a cause of travellers' diarrhoea, but it is also known to cause foodborne outbreaks. We report an outbreak of acute gastroenteritis caused by ETEC serotypes O92:H- and O153:H2 as well as Salmonella Anatum, which affected around 200 students and teachers after a high-school dinner in Greater Copenhagen, Denmark, November 2006. A retrospective cohort study showed that consumption of pasta salad with pesto was associated with an increased risk of illness (attack rate 59.4%; risk ratio 2.6, 95% confidence interval 1.2-5.7). Imported fresh basil used for preparation of the pesto was the most likely source of contamination. Although ETEC is associated with travellers' diarrhoea in Denmark, this outbreak suggests that a proportion of sporadic ETEC infections might be caused by contaminated imported foodstuffs. To improve food safety further, it is important to target this poorly regulated and researched area.

摘要

在工业化国家,产肠毒素大肠杆菌(ETEC)主要被诊断为旅行者腹泻的病因,但它也会引发食源性疾病暴发。我们报告了一起由ETEC血清型O92:H-和O153:H2以及鸭沙门氏菌引起的急性胃肠炎暴发事件,该事件于2006年11月在丹麦大哥本哈根的一次高中晚餐后影响了约200名学生和教师。一项回顾性队列研究表明,食用配有香蒜酱的意大利面沙拉会增加患病风险(发病率59.4%;风险比2.6,95%置信区间1.2 - 5.7)。用于制作香蒜酱的进口新鲜罗勒叶很可能是污染源。尽管在丹麦ETEC与旅行者腹泻有关,但此次暴发表明,一部分散发性ETEC感染可能是由受污染的进口食品引起的。为了进一步提高食品安全,针对这个监管不力且研究较少的领域很重要。

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