Pezzoli Lorenzo, Elson Richard, Little Christine L, Yip Hopi, Fisher Ian, Yishai Ruth, Anis Emilia, Valinsky Lea, Biggerstaff Matthew, Patel Nehal, Mather Henry, Brown Derek J, Coia John E, van Pelt Wilfrid, Nielsen Eva M, Ethelberg Steen, de Pinna Elizabeth, Hampton Michael D, Peters Tansy, Threlfall John
European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Control (ECDC), Stockholm, Sweden.
Foodborne Pathog Dis. 2008 Oct;5(5):661-8. doi: 10.1089/fpd.2008.0103.
Salmonella Senftenberg is uncommon in the United Kingdom. In January-June 2007, the Health Protection Agency reported on 55 primary human cases of Salmonella Senftenberg in England and Wales. In May 2007, fresh basil sold in the United Kingdom was found to be contaminated with Salmonella Senftenberg. We launched an investigation to elucidate the cause of this outbreak. Isolates were examined using plasmid profiling and pulsed-field gel electrophoresis, and the outbreak strain (SSFTXB.0014) was identified. We enquired via Enter-net whether other countries had isolated the outbreak strain, analyzed samples of fresh herbs from U.K. retailers, and interviewed patients on food history. Thirty-two patient-cases were referred to this outbreak in England and Wales. Onsets of illness occurred between 5 March and 6 June 2007. Fifty-six percent of patient-cases were females and 90% adults (>20 years old); three were admitted to hospital as a result of Salmonella infection. Scotland, Denmark, the Netherlands, and the United States reported on 19 cases of Salmonella Senftenberg infection presenting with the outbreak strain since January 2007. Eight samples of prepacked fresh basil imported from Israel tested positive with the same strain. A minority of patients could recall the consumption of basil before illness, and some reported consumption of products where basil was a likely ingredient. Environmental investigations in Israel did not identify the contamination source. Microbiological evidence suggested an association between contamination of fresh basil and the cases of Salmonella Senftenberg infection, leading to withdrawal of basil from all potentially affected batches from the U.K. market.
森夫滕贝格沙门氏菌在英国并不常见。2007年1月至6月，英国健康保护局报告了英格兰和威尔士55例原发性人类感染森夫滕贝格沙门氏菌的病例。2007年5月，英国销售的新鲜罗勒被发现受到森夫滕贝格沙门氏菌污染。我们展开了一项调查以查明此次疫情爆发的原因。通过质粒图谱分析和脉冲场凝胶电泳对分离菌株进行检测，并确定了疫情爆发菌株（SSFTXB.0014）。我们通过欧洲疾病预防控制中心网络询问其他国家是否分离出了该疫情爆发菌株，分析了英国零售商处的新鲜香草样本，并就患者的饮食史进行了访谈。英格兰和威尔士有32例患者被认定与此次疫情有关。发病时间在2007年3月5日至6月6日之间。56%的患者为女性，90%为成年人（>20岁）；3人因沙门氏菌感染入院治疗。苏格兰、丹麦、荷兰和美国报告称，自2007年1月以来，有19例感染森夫滕贝格沙门氏菌且呈现该疫情爆发菌株特征的病例。从以色列进口的8份预包装新鲜罗勒样本检测出该相同菌株呈阳性。少数患者能够回忆起发病前食用过罗勒，还有一些患者报告食用过可能含有罗勒的产品。在以色列进行的环境调查未确定污染源。微生物学证据表明新鲜罗勒污染与森夫滕贝格沙门氏菌感染病例之间存在关联，导致英国市场上所有可能受影响批次的罗勒下架。
