Molecular and Analytical Laboratory Center, Department of Food Technology, Faculty of Veterinary, Federal Fluminense University, Niterói, Brazil.
Post Graduate Program in Food Science Program, Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Appl Environ Microbiol. 2019 Jul 1;85(14). doi: 10.1128/AEM.00591-19. Print 2019 Jul 15.
spp. are among the most important foodborne pathogens and the third leading cause of human death among diarrheal diseases worldwide. Animals are the primary source of this pathogen, and animal-based foods are the main transmission route to humans. Thus, understanding the global epidemiology of serovars is key to controlling and monitoring this bacterium. In this context, this study aimed to evaluate the prevalence and diversity of serovars in animal-based foods (beef, pork, poultry, and seafood) throughout the five continents (Africa, the Americas [North and Latin America], Asia, Europe, and Oceania). The meta-analysis consisted of a chemometric assessment (hierarchical cluster analysis and principal component analysis) to identify the main epidemiological findings, including the prevalence and diversity of the serovars in each matrix. Regarding the serovar distribution, Typhimurium presented a cosmopolitan distribution, reported in all four assessed matrices and continents; poultry continues to play a central role in the dissemination of the Enteritidis serovar to humans, and Anatum and Weltevreden were the most frequently found in beef and seafood, respectively. Additionally, we recommended careful monitoring of certain serovars, such as Derby, Agona, Infantis, and Kentucky. Finally, given the scientific data regarding the most frequently reported serovars and which matrices constitute the main vehicles for the transmission of this pathogen, control programs may be improved, and specific interventions may be implemented in an attempt to reduce the risk of this pathogen reaching humans. Salmonellosis is caused by spp. and is the third leading cause of death among food-transmitted diseases. This pathogen is commonly disseminated in domestic and wild animals, and the infection's symptoms are characterized by acute fever, nausea, abdominal pain, and diarrhea. The animals are the primary source of salmonellae, and animal-based foods are the main transmission route to humans. Therefore, data collected from these sources could contribute to future global interventions for effective control and surveillance of along the food chain. In light of this, the importance of our research is in identifying the prevalence of serovars in four animal-based food matrices (pork, poultry, beef, and seafood) and to evaluate the importance that each matrix has as the primary source of this pathogen to humans.
血清型是最重要的食源性病原体之一，也是全球腹泻病导致人类死亡的第三大主要原因。动物是该病原体的主要来源，动物源性食品是人类感染的主要途径。因此，了解血清型的全球流行病学情况对于控制和监测该细菌至关重要。在这种情况下，本研究旨在评估五种大陆（非洲、美洲[北美和拉丁美洲]、亚洲、欧洲和大洋洲）的动物源性食品（牛肉、猪肉、家禽和海鲜）中血清型的流行情况和多样性。该荟萃分析包括化学计量评估（层次聚类分析和主成分分析），以确定主要的流行病学发现，包括每种基质中血清型的流行情况和多样性。关于血清型分布，鼠伤寒血清型呈现世界性分布，在所有评估的四种基质和四大洲均有报道；家禽继续在肠杆菌血清型向人类传播中发挥核心作用，而阿纳图姆和韦尔特维尔德分别是牛肉和海鲜中最常发现的血清型。此外，我们建议仔细监测某些血清型，如德比、阿贡纳、婴儿和肯塔基。最后，鉴于有关最常报告的血清型的科学数据以及构成该病原体主要传播媒介的基质，可改进控制方案，并实施具体干预措施，以减少该病原体传播给人类的风险。沙门氏菌病是由血清型引起的，是食源性疾病导致死亡的第三大原因。该病原体通常在家养和野生动物中传播，感染的症状表现为急性发热、恶心、腹痛和腹泻。动物是沙门氏菌的主要来源，动物源性食品是人类感染的主要途径。因此，从这些来源收集的数据可能有助于未来在全球范围内开展有效的控制和监测沿食物链传播的沙门氏菌的干预措施。有鉴于此，我们研究的重要性在于确定四种动物源性食品基质（猪肉、家禽、牛肉和海鲜）中血清型的流行情况，并评估每种基质作为人类感染该病原体的主要来源的重要性。
