Sanchez-Perez Gabino, Mira Alex, Nyiro Gábor, Pasić Lejla, Rodriguez-Valera Francisco
Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia, Canada.
Trends Genet. 2008 Apr;24(4):154-8. doi: 10.1016/j.tig.2008.01.002. Epub 2008 Mar 5.
When a bacterial species survives under changing environmental circumstances (e.g. salinity or temperature), its proteins might not function in all physicochemical conditions. We propose that prokaryotes cope with this problem by having two or more copies of the genes affected by environmental fluctuations, each one performing the same function under different conditions (i.e. ecoparalog). We identify potential examples in the bacterium Salinibacter ruber and in other species that experience wide environmental variations.
当一种细菌在不断变化的环境条件（如盐度或温度）下存活时，其蛋白质可能无法在所有物理化学条件下发挥作用。我们提出，原核生物通过拥有受环境波动影响的基因的两个或更多拷贝来应对这一问题，每个拷贝在不同条件下执行相同的功能（即生态旁系同源基因）。我们在红嗜盐菌及其他经历广泛环境变化的物种中发现了潜在的例子。
