Fleming Alfred J, Johansen Michael E
Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Medical Center, Columbus, Ohio 43210, USA.
Curr Opin Otolaryngol Head Neck Surg. 2008 Apr;16(2):127-34. doi: 10.1097/MOO.0b013e3282f4939a.
We reviewed articles published in the last 2 years on the subject of positron emission tomography (PET)/computed tomography (CT) use in head and neck cancer patients. The focus is on helping otolaryngologists decide when to use PET/CT and how to apply it to head and neck cancer patient management.
The main themes in the literature pertaining to PET/CT and head and neck cancer are use in untreated patients, evaluating early stage patients with N0 necks, use in cancer of unknown primary origin, detecting synchronous lesions and distant metastases, and use in previously treated patients.
Evidence is mounting in both otolaryngology and radiation oncology literature to support PET/CT as the preferred imaging modality for certain patients with head and neck cancer. We should consider PET/CT's superior accuracy and ability to improve patient management. It is our opinion that this imaging modality increases the otolaryngologist's and radiation oncologist's confidence when treating head and neck cancer patients and leads to appropriate management changes. Certainly, additional prospective trials would help validate these opinions.
我们回顾了过去两年发表的关于正电子发射断层扫描(PET)/计算机断层扫描(CT)在头颈癌患者中应用的文章。重点在于帮助耳鼻喉科医生决定何时使用PET/CT以及如何将其应用于头颈癌患者的管理。
文献中与PET/CT和头颈癌相关的主要主题包括在未经治疗的患者中的应用、评估颈部N0的早期患者、在原发灶不明的癌症中的应用、检测同步病变和远处转移以及在先前接受过治疗的患者中的应用。
耳鼻喉科和放射肿瘤学文献中的证据越来越多,支持PET/CT作为某些头颈癌患者的首选成像方式。我们应该考虑PET/CT的更高准确性和改善患者管理的能力。我们认为,这种成像方式在治疗头颈癌患者时会增加耳鼻喉科医生和放射肿瘤学家的信心,并导致适当的管理变化。当然,更多的前瞻性试验将有助于验证这些观点。