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假白喉棒状杆菌引起的皮肤感染:一份微生物学报告。

Cutaneous infection caused by Corynebacterium pseudodiphtheriticum: a microbiological report.

作者信息

Cantarelli Vlademir Vicente, Brodt Teresa Cristina Z, Secchi Carina, Inamine Everton, Pereira Fabiana de Souza

机构信息

Microbiology and Molecular Biology Sections, Weinmann Laboratório Ltda, Porto Alegre, RS, Brazil.

出版信息

Rev Inst Med Trop Sao Paulo. 2008 Jan-Feb;50(1):51-2. doi: 10.1590/s0036-46652008000100011.

DOI:10.1590/s0036-46652008000100011
PMID:18327488
Abstract

We report here a rare case of cutaneous infection due to Corynebacterium pseudodiphtheriticum. The patient presented to the clinical laboratory with a skin ulcer on his left leg. Gram-stained preparation of the purulent secretion revealed the presence of numerous rod-shaped Gram-positive organisms in the absence of any other species. The organism was grown in pure culture on sheep blood agar and was further identified as C. pseudodiphtheriticum using a commercial identification system (API-Coryne, BioMérieux, France). The infection was successfully treated with ciprofloxacin. This case emphasizes the importance of the clinical microbiology laboratory in correctly identifying Gram-positive organisms obtained in pure culture from skin ulcers.

摘要

我们在此报告一例罕见的由假白喉棒状杆菌引起的皮肤感染病例。该患者因左腿皮肤溃疡前往临床实验室就诊。脓性分泌物的革兰氏染色涂片显示存在大量杆状革兰氏阳性菌,未发现其他菌种。该菌在羊血琼脂上纯培养生长,并使用商业鉴定系统(API - Coryne,法国生物梅里埃公司)进一步鉴定为假白喉棒状杆菌。感染通过环丙沙星成功治愈。该病例强调了临床微生物学实验室在正确鉴定从皮肤溃疡中获得的纯培养革兰氏阳性菌方面的重要性。

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Cutaneous infection caused by Corynebacterium pseudodiphtheriticum: a microbiological report.假白喉棒状杆菌引起的皮肤感染:一份微生物学报告。
Rev Inst Med Trop Sao Paulo. 2008 Jan-Feb;50(1):51-2. doi: 10.1590/s0036-46652008000100011.
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假白喉棒状杆菌:假定的益生菌、机会性感染菌、新兴病原体。
Virulence. 2015;6(7):673-4. doi: 10.1080/21505594.2015.1067747.
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Recognition of Corynebacterium pseudodiphtheriticum by Toll-like receptors and up-regulation of antimicrobial peptides in human corneal epithelial cells.人角膜上皮细胞中Toll样受体对假白喉棒状杆菌的识别及抗菌肽的上调
Virulence. 2015;6(7):716-21. doi: 10.1080/21505594.2015.1066063. Epub 2015 Jun 30.