Craig T J, Maguire F E, Wallace M R
Department of Internal Medicine, Naval Hospital, San Diego, Calif. 92134-5000.
South Med J. 1991 Apr;84(4):504-6. doi: 10.1097/00007611-199104000-00026.
We have presented a case of tracheobronchitis due to C pseudodiphtheriticum in a patient with COPD who was treated with prednisone and apparently was not otherwise immunocompromised. Chronic lung disease seems to predispose to infection with C pseudodiphtheriticum; it can also occur in the immunocompetent host. This organism, when isolated in pure culture, should not be dismissed as a contaminant, but must be considered a possible etiologic agent. Sensitivity of diphtheroids to antibiotics is extremely variable. We believe vancomycin should be used in respiratory tract infections caused by diphtheroids, including C pseudodiphtheriticum, until the results of in vitro antibiotic susceptibility tests are available.
我们报告了一例慢性阻塞性肺疾病（COPD）患者因假白喉棒状杆菌引起气管支气管炎的病例，该患者接受了泼尼松治疗，且显然无其他免疫功能低下情况。慢性肺部疾病似乎易引发假白喉棒状杆菌感染；它也可发生于免疫功能正常的宿主。这种微生物在纯培养物中分离出来时，不应被当作污染物而忽略，而必须被视为一种可能的病原体。类白喉杆菌对抗生素的敏感性差异极大。我们认为，在获得体外抗生素药敏试验结果之前，对于包括假白喉棒状杆菌在内的类白喉杆菌引起的呼吸道感染，应使用万古霉素进行治疗。
