Ahmad Nadir, Zacharek Mark A
Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, 1313 21st Avenue South, Room 602, Nashville, TN 37232-4480, USA.
Otolaryngol Clin North Am. 2008 Apr;41(2):267-81, v. doi: 10.1016/j.otc.2007.11.010.
A relationship between allergic rhinitis and acute and chronic rhinosinusitis has been postulated for many years. Epidemiologic evidence suggests that such a relationship is likely. In addition, evidence of a common pathophysiologic mechanism linking these diseases is compelling and continues to evolve. Although a clear and definitive causal relationship remains to be elucidated, an increasing number of studies support the plausibility of this link. The current paradigm of the "unified airway" and evidence to support this model further strengthen this link. This article reviews the literature relating allergic rhinitis and acute and chronic rhinosinusitis.
多年来，人们一直假定变应性鼻炎与急慢性鼻-鼻窦炎之间存在关联。流行病学证据表明这种关联很可能存在。此外，将这些疾病联系起来的共同病理生理机制的证据令人信服，且仍在不断发展。尽管明确的因果关系仍有待阐明，但越来越多的研究支持了这种联系的合理性。当前的“统一气道”范式及支持该模型的证据进一步强化了这种联系。本文综述了有关变应性鼻炎与急慢性鼻-鼻窦炎的文献。
