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电视胸腔镜肺叶切除术:关于安全性、出院自理能力、疼痛及化疗耐受性的报告

Thoracoscopic lobectomy: report on safety, discharge independence, pain, and chemotherapy tolerance.

作者信息

Nicastri Daniel G, Wisnivesky Juan P, Litle Virginia R, Yun Jaime, Chin Cynthia, Dembitzer Francine R, Swanson Scott J

机构信息

Department of Surgery, Mount Sinai Medical Center, New York, NY 10029, USA.

出版信息

J Thorac Cardiovasc Surg. 2008 Mar;135(3):642-7. doi: 10.1016/j.jtcvs.2007.09.014.

Abstract

OBJECTIVE

Controversies regarding the safety, morbidity, and mortality of thoracoscopic lobectomy have prevented the widespread acceptance of the procedure. This series analyzed the safety, pain, analgesic use, and discharge disposition in patients who underwent thoracoscopic lobectomy and segmentectomy at a single institution.

METHODS

We collected data from 153 consecutive patients who underwent thoracoscopic (video-assisted thoracic surgery) lobectomy and assessed the perioperative outcomes, postoperative pain, and chemotherapy course. A total of 111 of 127 patients with lung cancer had stage I non-small cell lung cancer. The operative technique required 2 ports and an access incision (5-8 cm), individual hilar ligation, and lymph node dissection performed without rib-spreading devices.

RESULTS

There were 9 major complications (6%), including 1 perioperative death (0.7%). Conversion to thoracotomy occurred in 14 patients (9.2%). Blood transfusion was required in 11 patients (7%). The median chest tube time was 3 days, and the length of hospital stay was 4 days; 94.4% of patients went home at the time of discharge, and 5.6% of patients required a rehabilitation facility. At a median postsurgical follow-up time of 2 weeks, the mean postoperative pain score was 0.6 (0-3), 73% of patients did not use narcotics for pain control, and 47% of patients did not use any pain medication. Of patients receiving chemotherapy (N = 26), 73% completed a full course on schedule and 85% received all intended cycles.

CONCLUSION

Thoracoscopic (video-assisted thoracic surgery) lobectomy can be performed safely. Discharge independence and low pain estimates in the early postoperative period suggest that this approach may be beneficial. Furthermore, there is a trend toward improved tolerance of chemotherapy.

摘要

目的

关于胸腔镜肺叶切除术的安全性、发病率和死亡率的争议阻碍了该手术的广泛应用。本系列研究分析了在单一机构接受胸腔镜肺叶切除术和肺段切除术患者的安全性、疼痛情况、镇痛药物使用及出院安排。

方法

我们收集了153例连续接受胸腔镜(电视辅助胸腔手术)肺叶切除术患者的数据,并评估围手术期结局、术后疼痛及化疗过程。127例肺癌患者中,共有111例为Ⅰ期非小细胞肺癌。手术技术需要2个切口和一个辅助切口(5 - 8厘米),进行个体化肺门结扎,并在不使用肋骨撑开器的情况下进行淋巴结清扫。

结果

发生9例严重并发症(6%),包括1例围手术期死亡(0.7%)。14例患者(9.2%)中转开胸。11例患者(7%)需要输血。胸腔引流管留置时间中位数为3天,住院时间为4天;94.4%的患者出院时回家,5.6%的患者需要康复机构护理。术后中位随访时间为2周时,术后平均疼痛评分为0.6(0 - 3),73%的患者未使用麻醉药物控制疼痛,47%的患者未使用任何止痛药物。在接受化疗的患者中(N = 26),73%的患者按计划完成了整个疗程,85%的患者接受了所有预定周期的化疗。

结论

胸腔镜(电视辅助胸腔手术)肺叶切除术可安全实施。出院时无需他人帮助以及术后早期疼痛程度较低表明这种手术方式可能有益。此外,化疗耐受性有改善趋势。

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