• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

与头颈部放疗相关的拔牙:单一机构的十年经验

Dental extractions related to head and neck radiotherapy: ten-year experience of a single institution.

作者信息

Koga Daniel Henrique, Salvajoli João Victor, Kowalski Luiz Paulo, Nishimoto Ines N, Alves Fabio Abreu

机构信息

Stomatology Department, A.C. Camargo Hospital, São Paulo, Brazil.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 May;105(5):e1-6. doi: 10.1016/j.tripleo.2008.01.007. Epub 2008 Mar 10.

DOI:10.1016/j.tripleo.2008.01.007
PMID:18329909
Abstract

OBJECTIVE

This study evaluates the frequency of osteoradionecrosis associated with dental extractions.

STUDY DESIGN

A total of 405 patients submitted to radiotherapy and had dental extractions were evaluated. The patients were divided into 3 groups.

RESULTS

In group 1, 316 patients were submitted to 1.647 dental extractions (mean 5.2 teeth per patient) and in another 47 patients the number of teeth removed was not clearly reported. Group 2 comprised 5 patients who had 33 teeth extracted (mean 6.6 each). In group 3, 55 patients had 290 teeth removed (mean 5.3 each) and in another 2 patients the number of dental extractions could not be established. In general, only 3 cases of osteoradionecrosis related to dental extractions were observed: 2 related to exodontias performed before and 1 after radiotherapy.

CONCLUSIONS

The low prevalence of osteoradionecrosis found in this work suggests the possibility of performing exodontias after radiotherapy by experienced dentists in the management of head and neck cancer.

摘要

目的

本研究评估与拔牙相关的放射性骨坏死的发生率。

研究设计

共评估了405例接受放疗并拔牙的患者。这些患者被分为3组。

结果

第1组,316例患者接受了1647次拔牙(平均每位患者5.2颗牙),另有47例患者拔除牙齿的数量未明确报告。第2组包括5例患者,共拔除33颗牙(平均每位患者6.6颗)。第3组,55例患者拔除290颗牙(平均每位患者5.3颗),另有2例患者的拔牙数量无法确定。总体而言,仅观察到3例与拔牙相关的放射性骨坏死病例:2例与放疗前拔牙有关,1例与放疗后拔牙有关。

结论

本研究中发现的放射性骨坏死低发生率表明,在头颈部癌症的治疗中,经验丰富的牙医在放疗后进行拔牙是有可能的。

相似文献

1
Dental extractions related to head and neck radiotherapy: ten-year experience of a single institution.与头颈部放疗相关的拔牙:单一机构的十年经验
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 May;105(5):e1-6. doi: 10.1016/j.tripleo.2008.01.007. Epub 2008 Mar 10.
2
Osteoradionecrosis of the jaws as a side effect of radiotherapy of head and neck tumour patients--a report of a thirty year retrospective review.颌骨放射性骨坏死作为头颈部肿瘤患者放疗的副作用——一项30年回顾性研究报告
Int J Oral Maxillofac Surg. 2003 Jun;32(3):289-95. doi: 10.1054/ijom.2002.0332.
3
Retrospective audit of the use of the Marx Protocol for prophylactic hyperbaric oxygen therapy in managing patients requiring dental extractions following radiotherapy to the head and neck.对马克思方案在对头颈部放疗后需要拔牙的患者进行预防性高压氧治疗中的应用进行回顾性审计。
N Z Dent J. 2009 Jun;105(2):47-50.
4
Dental extractions and radiotherapy in head and neck oncology: review of the literature.口腔颌面-头颈部肿瘤的拔牙与放射治疗:文献综述
Oral Dis. 2008 Jan;14(1):40-4. doi: 10.1111/j.1601-0825.2006.01351.x.
5
Relationship between oral health status and development of osteoradionecrosis of the mandible: a retrospective longitudinal study.口腔健康状况与下颌骨放射性骨坏死发生之间的关系:一项回顾性纵向研究。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Jun;105(6):731-8. doi: 10.1016/j.tripleo.2007.10.011. Epub 2008 Mar 10.
6
Do pre-irradiation dental extractions reduce the risk of osteoradionecrosis of the mandible?放疗前拔牙能否降低下颌骨放射性骨坏死的风险?
Head Neck. 2007 Jun;29(6):528-36. doi: 10.1002/hed.20538.
7
Dental extractions in the irradiated head and neck patient: a retrospective analysis of Memorial Sloan-Kettering Cancer Center protocols, criteria, and end results.头颈部放疗患者的拔牙治疗:纪念斯隆凯特琳癌症中心方案、标准及最终结果的回顾性分析
J Oral Maxillofac Surg. 2003 Oct;61(10):1123-31. doi: 10.1016/s0278-2391(03)00669-4.
8
Jaw osteoradionecrosis and dental extraction after head and neck radiotherapy: A nationwide population-based retrospective study in Taiwan.头颈部放疗后颌骨放射性骨坏死与拔牙:台湾一项基于全国人口的回顾性研究
Oral Oncol. 2016 May;56:71-7. doi: 10.1016/j.oraloncology.2016.03.005. Epub 2016 Mar 28.
9
Osteoradionecrosis of the jaw bones at the University of Kentucky Medical Center.肯塔基大学医学中心的颌骨放射性骨坏死
J Ky Med Assoc. 1989 Jul;87(7):327-31.
10
A practical guide for patients undergoing exodontias following radiotherapy to the oral cavity.口腔放疗后接受拔牙术患者实用指南。
Dent Update. 2003 Jul-Aug;30(6):338.

引用本文的文献

1
Survey of experiences and barriers to dental care post-head and neck cancer in OraRad study participants.口腔癌患者接受头颈部癌症治疗后面临的口腔护理体验和障碍调查。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2023 Apr;135(4):501-509. doi: 10.1016/j.oooo.2022.11.011. Epub 2022 Dec 13.
2
Risk factors for osteoradionecrosis of the jaw in patients with oral or oropharyngeal cancer: Verification of the effect of tooth extraction before radiotherapy using propensity score matching analysis.口腔或口咽癌患者颌骨放射性骨坏死的危险因素:使用倾向评分匹配分析验证放疗前拔牙的效果。
J Dent Sci. 2022 Apr;17(2):1024-1029. doi: 10.1016/j.jds.2021.10.019. Epub 2021 Nov 20.
3
Antibiotic therapy for the prevention of osteoradionecrosis following tooth extraction in head-and-neck cancer patients postradiotherapy: An 11-year retrospective study.
抗生素治疗对头颈部癌症放疗后拔牙患者放射性骨坏死的预防作用:一项11年的回顾性研究。
Natl J Maxillofac Surg. 2021 Sep-Dec;12(3):333-338. doi: 10.4103/njms.njms_413_21. Epub 2021 Dec 13.
4
Tooth Failure Post-Radiotherapy in Head and Neck Cancer: Primary Report of the Clinical Registry of Dental Outcomes in Head and Neck Cancer Patients (OraRad) Study.头颈部癌症放疗后牙齿缺失:头颈部癌症患者口腔结局临床登记研究(OraRad 研究)的初步报告。
Int J Radiat Oncol Biol Phys. 2022 Jun 1;113(2):320-330. doi: 10.1016/j.ijrobp.2021.11.021. Epub 2021 Dec 5.
5
Exposed bone in patients with head and neck cancer treated with radiation therapy: An analysis of the Observational Study of Dental Outcomes in Head and Neck Cancer Patients (OraRad).头颈部癌症患者接受放射治疗后暴露的骨头:头颈部癌症患者口腔结局观察性研究(OraRad)的分析。
Cancer. 2022 Feb 1;128(3):487-496. doi: 10.1002/cncr.33948. Epub 2021 Oct 19.
6
Leukocyte- and platelet-rich fibrin does not provide any additional benefit for tooth extraction in head and neck cancer patients post-radiotherapy: a randomized clinical trial.富含白细胞和血小板的纤维蛋白在头颈部癌症患者放疗后拔牙中不提供任何额外益处:一项随机临床试验。
Med Oral Patol Oral Cir Bucal. 2020 Nov 1;25(6):e799-e804. doi: 10.4317/medoral.23804.
7
Protection of wear resistance behaviour of enamel against electron beam irradiation.牙釉质耐磨性能免受电子束辐照的保护作用。
BDJ Open. 2019 Jul 11;5:11. doi: 10.1038/s41405-019-0021-0. eCollection 2019.
8
The association between dental therapy timelines and osteoradionecrosis: a nationwide population-based cohort study.牙科治疗时间安排与放射性骨坏死的相关性:一项全国范围内基于人群的队列研究。
Clin Oral Investig. 2020 Jan;24(1):455-463. doi: 10.1007/s00784-019-02866-4. Epub 2019 May 20.
9
Retrospective study of osteoradionecrosis in the jaws of patients with head and neck cancer.头颈部癌症患者颌骨放射性骨坏死的回顾性研究。
J Korean Assoc Oral Maxillofac Surg. 2019 Feb;45(1):21-28. doi: 10.5125/jkaoms.2019.45.1.21. Epub 2019 Feb 26.
10
Influence of dental treatment in place on quality of life in oral cancer patients undergoing chemoradiotherapy.口腔癌患者放化疗期间口腔内现有治疗对生活质量的影响
Med Oral Patol Oral Cir Bucal. 2018 Jul 1;23(4):e498-e505. doi: 10.4317/medoral.22353.