Lombion Sandrine, Comte Alexandre, Tatu Laurent, Brand Gérard, Moulin Thierry, Millot Jean-Louis
Laboratoire de Neurosciences Intégratives et Cliniques, 1 Place Leclerc, Université de Franche-Comté, 25030 Besançon Cedex, France.
Hum Brain Mapp. 2009 Mar;30(3):821-8. doi: 10.1002/hbm.20548.
It is well known that most odorants stimulate both the olfactory system and the trigeminal system. However, the overlap between the brain processes involved in each of these sensorial perceptions is still poorly documented. This study aims to compare fMRI brain activations while smelling two odorants of a similar perceived intensity and pleasantness: phenyl ethyl alcohol (a pure olfactory stimulus) and iso-amyl-acetate (a bimodal olfactory-trigeminal stimulus) in a homogeneous sample of 15 healthy, right-handed female subjects. The analysis deals with the contrasts of brain activation patterns between these two odorant conditions. The results showed a significant recruitment of the right insular cortex, and bilaterally in the cingulate in response to the trigeminal component. These findings are discussed in relation to the characteristics of these odorants compared with those tested in previous studies.
众所周知，大多数气味剂会同时刺激嗅觉系统和三叉神经系 统。然而，参与这两种感官认知的大脑过程之间的重叠情况仍鲜有文献记载。本研究旨在比较15名健康右利手女性受试者在闻两种强度和愉悦度相似的气味剂时的功能磁共振成像（fMRI）大脑激活情况：苯乙醇（一种纯粹的嗅觉刺激物）和异戊酸乙酯（一种嗅觉 - 三叉神经双模态刺激物）。分析涉及这两种气味剂条件下大脑激活模式的对比。结果显示，右侧岛叶皮质以及双侧扣带回因三叉神经成分而出现显著激活。结合与先前研究中测试的气味剂特性相比，对这些发现进行了讨论。
