McBride M O, Smye M, Nesbitt G S, Hadden D R
Sir George E. Clark Metabolic Unit, Royal Victoria Hospital, Belfast, UK.
Diabet Med. 1991 Aug-Sep;8(7):688-90. doi: 10.1111/j.1464-5491.1991.tb01679.x.
The use of a reagent strip and reflectance meter for the bedside measurement of 3-hydroxybutyrate during the clinical management of diabetic ketoacidosis is described. Comparison of this method with a laboratory enzymatic assay shows good correlation (r = 0.97, p less than 0.05). Initial use in acute ketoacidosis suggests that knowledge of hourly changes in 3-hydroxybutyrate levels could be helpful in determining the optimum insulin dose.
