在对日历时间段、喷洒天数以及在东南亚停留时间进行调整后，“牧场工行动”退伍军人中的糖尿病与癌症情况。
Diabetes and cancer in veterans of Operation Ranch Hand after adjustment for calendar period, days of spraying, and time spent in Southeast Asia.
作者信息
Michalek Joel E, Pavuk Marian
机构信息
Department of Epidemiology and Biostatistics, University of Texas Health Science Center at San Antonio, Texas 78229, USA.
出版信息
J Occup Environ Med. 2008 Mar;50(3):330-40. doi: 10.1097/JOM.0b013e31815f889b.
BACKGROUND
The Air Force Health Study was launched in 1980 as part of a Federal effort to resolve the Agent Orange issue.
OBJECTIVES
To study diabetes and cancer with additional adjustment for days of spraying, calendar period of service, and time spent in Southeast Asia (SEA).
METHODS
This was a longitudinal study of veterans of Operation Ranch Hand, the unit responsible for spraying Agent Orange and other 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-contaminated herbicides in Vietnam from 1962 to 1971.
RESULTS
Associations between TCDD and diabetes and between TCDD and cancer in Ranch Hand veterans are strengthened after adjustment for calendar period of service, days of spraying, and, for cancer, time spent in SEA.
CONCLUSIONS
Calendar period of service, days of spraying, and time spent in SEA are important confounders in the Air Force Health Study.
背景
空军健康研究于1980年启动，是联邦政府解决橙剂问题工作的一部分。
目的
研究糖尿病和癌症，并对喷洒天数、服役日历期以及在东南亚（SEA）的停留时间进行额外调整。
方法
这是一项对“牧场工人行动”退伍军人的纵向研究，该部队负责在1962年至1971年期间在越南喷洒橙剂和其他受2,3,7,8-四氯二苯并对二恶英（TCDD）污染的除草剂。
结果
在对服役日历期、喷洒天数以及（对于癌症）在SEA的停留时间进行调整后，“牧场工人行动”退伍军人中TCDD与糖尿病之间以及TCDD与癌症之间的关联得到加强。
结论
服役日历期、喷洒天数以及在SEA的停留时间是空军健康研究中的重要混杂因素。
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