Sen Jyotsna, Choudhary Lalita, Marwah Sanjay, Godara Rajesh, Marwah Nisha, Sen Rajiv
Department of Radiodiagnosis, Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India.
Asian J Surg. 2008 Jan;31(1):16-9. doi: 10.1016/S1015-9584(08)60049-4.
This prospective study was undertaken to evaluate the role of colour Doppler sonography in the assessment of prostate carcinoma.
Forty consecutive patients who were suspected of having prostate carcinoma with either raised prostate specific antigen or abnormal digital rectal examination were included in the study. Transrectal greyscale and colour Doppler sonography of the prostate was performed using a 5-9 MHz intracavitary probe. Needle biopsies were taken from areas that showed increased flow on colour Doppler. The results were correlated with the final diagnosis established on histopathological examination.
Comparison of greyscale and colour Doppler sonography showed that the latter is more sensitive and specific in predicting the malignancy. The statistical parameters of colour Doppler versus grayscale sonography were: sensitivity 88.23 vs. 73.52, specificity 66.66 vs. 33.33, positive predictive value 93.75 vs. 85.18, and negative predictive value 50 vs. 22.22, respectively.
Colour Doppler and greyscale sonography should be routinely performed to improve detection of prostate carcinoma and to target the lesion.
本前瞻性研究旨在评估彩色多普勒超声在前列腺癌评估中的作用。
连续纳入40例因前列腺特异性抗原升高或直肠指检异常而疑似患有前列腺癌的患者。使用5-9MHz腔内探头对前列腺进行经直肠灰阶和彩色多普勒超声检查。从彩色多普勒显示血流增加的区域进行穿刺活检。结果与组织病理学检查确定的最终诊断进行相关性分析。
灰阶超声与彩色多普勒超声的比较显示，后者在预测恶性肿瘤方面更敏感、更具特异性。彩色多普勒超声与灰阶超声的统计参数分别为：敏感性88.23对73.52，特异性66.66对33.33，阳性预测值93.75对85.18，阴性预测值50对22.22。
应常规进行彩色多普勒和灰阶超声检查，以提高前列腺癌的检测率并确定病变部位。
