Ukpong D I, Ugboko V I, Ndukwe K C, Gbolahan O O
Department of Mental Health, Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria.
Br J Oral Maxillofac Surg. 2008 Jun;46(4):297-300. doi: 10.1016/j.bjoms.2007.09.013. Epub 2008 Mar 11.
We examined the health-related quality of life (HR QoL) of patients with facial trauma and compared it with that of healthy controls; temporal changes in HR QoL of patients over 12 weeks compared with baseline values; and whether the risk of depression could be identified by baseline HR QoL. For 26 months we recruited 126 consecutive patients with facial injuries and 126 age and sex-matched healthy controls for the study. Enrollment criteria included age 18 years and over, Glasgow coma scale score on admission of 12 and over, and duration of stay of more than 24 hours. HR QoL was measured using the 26-item World Health Organization Quality of Life Questionnaire (WHO QoL-Bref), and depression was measured with the Hospital Anxiety and Depression Scale (HADS). Scores in all domains of the WHO QoL-Bref (physical, psychological, social relations, and environment) were considerably reduced in injured patients compared with controls. During follow up there were improvements only in the domains of physical health and environment, but not in psychological health. There was a significant reduction in the HR QoL domain of social relationships with time. The regression equation for all four QoL domains as predictors was significantly related to depression scores throughout the study period. Patients with facial injuries are at risk of poor QoL after trauma. There was a high incidence of depression throughout the follow-up period, and poor QoL at baseline predicted depression during follow-up.
我们研究了面部创伤患者的健康相关生活质量(HR QoL),并将其与健康对照组进行比较;比较了患者12周内HR QoL相对于基线值的时间变化;以及基线HR QoL是否能够识别出抑郁风险。在26个月的时间里,我们连续招募了126例面部损伤患者和126例年龄及性别匹配的健康对照者进行研究。纳入标准包括年龄18岁及以上、入院时格拉斯哥昏迷量表评分12分及以上、住院时间超过24小时。使用26项世界卫生组织生活质量问卷(WHO QoL-Bref)测量HR QoL,使用医院焦虑抑郁量表(HADS)测量抑郁情况。与对照组相比,受伤患者WHO QoL-Bref所有领域(生理、心理、社会关系和环境)的得分均显著降低。在随访期间,仅生理健康和环境领域有所改善,心理健康领域未见改善。社会关系的HR QoL领域得分随时间显著降低。在整个研究期间,以所有四个生活质量领域作为预测指标的回归方程与抑郁得分显著相关。面部损伤患者创伤后存在生活质量差的风险。在整个随访期间抑郁发生率较高,基线时生活质量差可预测随访期间的抑郁情况。