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多发性硬化症急性复发时的疲劳:主观与客观评估

Fatigue in multiple sclerosis presenting as acute relapse: subjective and objective assessment.

作者信息

Flachenecker Peter, Meissner Heike

机构信息

Neurological Rehabilitation Center Quellenhof, D-75323 Bad Wildbad, Germany.

出版信息

Mult Scler. 2008 Mar;14(2):274-7. doi: 10.1177/1352458507082480.

DOI:10.1177/1352458507082480
PMID:18337428
Abstract

We report on a patient with multiple sclerosis (MS) who presented with fatigue as the only manifestation of an acute MS relapse. Fatigue was assessed by the 'Würzburg Fatigue Inventory in MS (WEIMuS)' scale and confirmed by neuropsychological testing of attention. After high-dose corticosteroid therapy, subjective symptoms were completely abolished. The improvement was corroborated by both, the WEIMuS score and neuropsychological testing. MS-related fatigue may be the only symptom of an acute MS relapse, and neuropsychological methods may be used to objectively assess and follow the time course of this common and disabling symptom.

摘要

我们报告了一名患有多发性硬化症(MS)的患者,其急性MS复发的唯一表现为疲劳。通过“维尔茨堡MS疲劳量表(WEIMuS)”对疲劳进行评估,并通过注意力的神经心理学测试予以证实。高剂量皮质类固醇治疗后,主观症状完全消失。WEIMuS评分和神经心理学测试均证实了这种改善。MS相关疲劳可能是急性MS复发的唯一症状,神经心理学方法可用于客观评估并跟踪这种常见且致残症状的病程。

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