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没食子树:一种控制耐甲氧西林金黄色葡萄球菌感染的候选植物。

Quercus infectoria: a candidate for the control of methicillin-resistant Staphylococcus aureus infections.

作者信息

Chusri S, Voravuthikunchai S P

机构信息

Department of Microbiology, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand.

出版信息

Phytother Res. 2008 Apr;22(4):560-2. doi: 10.1002/ptr.2377.

DOI:10.1002/ptr.2377
PMID:18338770
Abstract

Acetone, ethyl acetate, 95% ethanol and aqueous extracts of Quercus infectoria (Q. infectoria) demonstrated significant antibacterial activities against all strains of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible Staphylococcus aureus (MSSA). Inhibition zones were in the range 11.75-16.82 mm. Both MRSA and MSSA strains exhibited minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values at 0.13 and 0.13-1.00 mg/mL, respectively. At 2 MIC, the growth of two representative MRSA strains was continually inhibited for at least 20 h. Surviving MRSA cells were not detected within 12-14 h after treatment with the extract at 4 MIC concentration. Staphylococcus aureus ATCC 25923 demonstrated similar results.

摘要

丙酮、乙酸乙酯、95%乙醇以及没食子(Quercus infectoria)水提取物对所有耐甲氧西林金黄色葡萄球菌(MRSA)菌株和甲氧西林敏感金黄色葡萄球菌(MSSA)菌株均表现出显著的抗菌活性。抑菌圈范围为11.75 - 16.82毫米。MRSA和MSSA菌株的最低抑菌浓度(MIC)和最低杀菌浓度(MBC)值分别为0.13和0.13 - 1.00毫克/毫升。在2倍MIC浓度下,两种代表性MRSA菌株的生长至少持续被抑制20小时。在4倍MIC浓度的提取物处理后12 - 14小时内未检测到存活的MRSA细胞。金黄色葡萄球菌ATCC 25923也显示出类似结果。

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