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孕期自助戒烟干预措施:一项系统评价与荟萃分析。

Self-help smoking cessation interventions in pregnancy: a systematic review and meta-analysis.

作者信息

Naughton Felix, Prevost A Toby, Sutton Stephen

机构信息

General Practice and Primary Care Research Unit, Institute of Public Health, University of Cambridge, Cambridge, UK.

出版信息

Addiction. 2008 Apr;103(4):566-79. doi: 10.1111/j.1360-0443.2008.02140.x.

Abstract

AIMS

Self-help smoking cessation interventions for pregnant smokers are of importance due to their potential to be wide-reaching, low-cost and their appeal to pregnant smokers who are interested in quitting smoking. To date, however, there has been no systematic assessment of their efficacy. This systematic review aimed to assess the efficacy of self-help interventions for pregnant smokers and to investigate whether self-help material intensity, type or delivery are associated with cessation.

METHODS

The literature was searched for randomized and quasi-randomized controlled trials of self-help smoking cessation interventions for pregnant smokers without significant cessation counselling. Fifteen trials met the inclusion criteria and relevant data were extracted independently.

RESULTS

The primary meta-analysis pooled 12 trials comparing usual care (median quit rate 4.9%) with self-help (median quit rate 13.2%) and yielded a pooled odds ratio (OR) of 1.83 [95% confidence interval (CI) 1.23-2.73], indicating that self-help interventions on average nearly double the odds of quitting compared with standard care. However, a further meta-analysis failed to find evidence that intervention materials of greater intensity increase quitting significantly over materials of lesser intensity (pooled OR = 1.25, 95% CI 0.81-1.94). There was insufficient evidence to determine whether the tailoring of materials or levels of one-to-one contact were related to intervention efficacy.

CONCLUSIONS

Self-help interventions appear to be more effective than standard care although, due mainly to a lack of trials, it is unclear whether more sophisticated and intensive approaches increase intervention effectiveness.

摘要

目的

针对怀孕吸烟者的自助戒烟干预措施具有重要意义,因为它们有可能广泛实施、成本低廉,并且对有戒烟意愿的怀孕吸烟者具有吸引力。然而,迄今为止,尚未对其疗效进行系统评估。本系统评价旨在评估针对怀孕吸烟者的自助干预措施的疗效,并调查自助材料的强度、类型或交付方式是否与戒烟有关。

方法

检索文献,查找针对怀孕吸烟者的自助戒烟干预措施的随机和半随机对照试验,且不包括重大戒烟咨询。15项试验符合纳入标准,并独立提取相关数据。

结果

主要的荟萃分析汇总了12项试验,比较了常规护理(中位戒烟率4.9%)与自助干预(中位戒烟率13.2%),得出汇总优势比(OR)为1.83 [95%置信区间(CI)1.23 - 2.73],表明与标准护理相比,自助干预平均使戒烟几率几乎翻倍。然而,进一步的荟萃分析未能找到证据表明强度更大的干预材料比强度较小的材料能显著提高戒烟率(汇总OR = 1.25,95% CI 0.81 - 1.94)。没有足够的证据来确定材料的定制或一对一接触的程度是否与干预效果相关。

结论

自助干预似乎比标准护理更有效,不过,主要由于试验数量不足,尚不清楚更复杂和强化的方法是否会提高干预效果。

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