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[使用泥炭和腐殖酸成功预防粘连]

[Successful prevention of adhesions using peat and humic acids].

作者信息

Mesrogli M, Maas D H, Mauss B, Plogmann S, Ziechmann W, Schneider J

机构信息

Frauenklinik, Medizinischen Hochschule Hannover.

出版信息

Zentralbl Gynakol. 1991;113(10):583-90.

PMID:1833933
Abstract

In order to verify the adhesion preventing capability of peat and peat components, 180 female rats were subjected to therapeutic bathing after standardised lesions had been placed on both uterine horns and the peritoneum of the anterior abdominal wall. From the 3rd and 7th day after surgery, respectively, randomized groups of animals consisting of 20 animals each were bathed in tap water, pure fresh peat, peat solution after pressing, centrifugation and filtration, and a solution of humic acids extracted from peat, all at the same temperature. One week after bathing for three weeks, the rats were relaparotomized, and quality and degree of the adhesions found were documented. Significant less and minor (p less than 0.001) adhesions were found in animals bathed in humic acid solution compared to the animals which had not been bathed at all. Peat solution and fresh peat reduced the formation of adhesions significantly, too, while warm water baths did not show any antiadhesive effect. Our results suggest humic acids to be the most effective component of peat with regard to the prevention of adhesions.

摘要

为了验证泥炭及其成分的防粘连能力,在180只雌性大鼠的双侧子宫角和前腹壁腹膜制造标准化损伤后,对其进行治疗性洗浴。分别在术后第3天和第7天,将每组20只动物的随机分组,分别置于相同温度的自来水中、纯新鲜泥炭、压榨、离心和过滤后的泥炭溶液以及从泥炭中提取的腐殖酸溶液中进行洗浴。在为期三周的洗浴一周后,再次对大鼠进行剖腹手术,并记录发现的粘连质量和程度。与未进行任何洗浴的动物相比,用腐殖酸溶液洗浴的动物体内粘连明显更少且程度更轻(p小于0.001)。泥炭溶液和新鲜泥炭也显著减少了粘连的形成,而温水浴则未显示出任何抗粘连效果。我们的结果表明,就预防粘连而言,腐殖酸是泥炭中最有效的成分。

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