Pinto Pabón Isabel, Magret Javier Porras, Unzurrunzaga Elena Ayerbe, García Isidro Millán, Catalán Isidoro Bruna, Cano Vieco M Luisa
Department of Interventional Radiology, Hospital de Madrid, Montepríncipe, Madrid, Spain.
Fertil Steril. 2008 Dec;90(6):2356-60. doi: 10.1016/j.fertnstert.2007.10.074. Epub 2008 Mar 12.
To evaluate pregnancies in women who had previously undergone uterine fibroid embolization.
Prospective study.
A city hospital in Spain.
PATIENT(S): A cohort of 100 uterine fibroid embolization patients, 57 of whom wished to preserve their fertility.
INTERVENTION(S): Uterine arteries were embolized by using 500-1,200 microm tris-acryl gelatin microspheres. After intervention, patient follow-up was performed at 1 week, 3 months, 6 months, and yearly.
MAIN OUTCOME MEASURE(S): The number of pregnancies and course of pregnancy.
RESULT(S): Eleven pregnancies in 10 women (19.2%). The pregnancies resulted in 8 live births, including 4 normal and 4 cesarean deliveries. Early miscarriage occurred in 3 cases (2 patients). None of the 8 newborns was a low-birth weight infant, and gestation lasted >or=37 weeks in all the patients, except for 1 case of a macrosomic fetus delivered at 33 weeks. There were no cases of abnormal placental implantation.
CONCLUSION(S): Despite the small sample size, uterine artery embolization appears to be viable in young women who still want to become pregnant. Larger series and studies comparing uterine fibroid embolization and myomectomy are needed.
评估既往接受过子宫肌瘤栓塞术的女性的妊娠情况。
前瞻性研究。
西班牙一家城市医院。
100例子宫肌瘤栓塞术患者队列，其中57例希望保留生育能力。
使用500 - 1200微米的三丙烯酸明胶微球栓塞子宫动脉。干预后，在1周、3个月、6个月及每年对患者进行随访。
妊娠次数及妊娠过程。
10名女性中有11次妊娠（19.2%）。这些妊娠共分娩8名活产婴儿，包括4例顺产和4例剖宫产。3例（2名患者）发生早期流产。8名新生儿均非低体重儿，除1例33周分娩的巨大胎儿外，所有患者的妊娠期均≥37周。无胎盘植入异常病例。
尽管样本量较小，但子宫动脉栓塞术对于仍希望怀孕的年轻女性似乎是可行的。需要更大规模的系列研究以及比较子宫肌瘤栓塞术和子宫肌瘤切除术的研究。
