Jansen P H, van Dijck J A, Verbeek A L, Durian F W, Joosten E M
Division Neuromuscular Diseases, Catholic University of Nijmegen, The Netherlands.
Eur Arch Psychiatry Clin Neurosci. 1991;241(2):102-4. doi: 10.1007/BF02191150.
A nationwide two-phase survey was carried out of the adult population of the Netherlands regarding fasciculation, muscle pain and muscle cramp. We conducted a population-based telephone interview with 780 Dutch adults, followed by a questionnaire covering more clinical details, filled out by 311 subjects, who had been interviewed by telephone previously. From these data the frequencies of fasciculation (men 50%, women 61%), muscle cramp (men 28%, women 42%) and muscle pain (men 48%, women 60%) in the Dutch adult population in 1988 were estimated. The combined occurrence of frequent fasciculation and frequent muscle cramp as well as of frequent fasciculation and frequent muscle pain was reported only sporadically. Although the muscular pain-fasciculation syndrome and the muscular cramp-fasciculation syndrome represent combinations of common neuromuscular phenomena, their occurrence in the general population proved to be rare. This finding supports their clinical identity as distinct motor unit hyperactivity syndromes rather than mere coincidences of fasciculation, muscle cramp and muscle pain.
针对荷兰成年人群体的肌束震颤、肌肉疼痛和肌肉痉挛情况，开展了一项全国性的两阶段调查。我们对780名荷兰成年人进行了基于人群的电话访谈，随后，由311名此前接受过电话访谈的受试者填写了一份涵盖更多临床细节的问卷。根据这些数据，估算了1988年荷兰成年人群体中肌束震颤（男性50%，女性61%）、肌肉痉挛（男性28%，女性42%）和肌肉疼痛（男性48%，女性60%）的发生率。频繁肌束震颤与频繁肌肉痉挛以及频繁肌束震颤与频繁肌肉疼痛的合并发生情况仅有零星报告。尽管肌肉疼痛-肌束震颤综合征和肌肉痉挛-肌束震颤综合征是常见神经肌肉现象的组合，但它们在普通人群中的发生情况实属罕见。这一发现支持了它们作为独特的运动单位活动亢进综合征的临床特征，而非仅仅是肌束震颤、肌肉痉挛和肌肉疼痛的巧合。
