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循环性精神病的结婚率与生育率:与情感障碍、精神分裂症及普通人群的比较

Marriage rate and fertility in cycloid psychosis: comparison with affective disorder, schizophrenia and the general population.

作者信息

Jönsson S A

出版信息

Eur Arch Psychiatry Clin Neurosci. 1991;241(2):119-25. doi: 10.1007/BF02191155.

Abstract

A cohort of patients with cycloid psychosis (n = 34) admitted to hospital for the first time in 1925 was compared with affective patients (n = 30) and schizophrenic patients (n = 81) admitted at the same time as well as with the general population in the catchment area. The marriage rate in cycloid probands was in accordance with that of the general population at index admission. Five years later it was significantly lower than expected, but after 10 years the marriage rate was statistically in accordance with expected figures. Fertility was significantly higher than in schizophrenic probands (P less than 0.001). Fertility in cycloid women was in accordance with expected figures based on the mean fertility of birth cohorts of women. It was, however, significantly lower than expected, both in affective women (P less than 0.05) and in schizophrenic women (P less than 0.0001). Prepsychotic fertility (before the index episode) did not significantly diverge from expected figures in cycloid women. It was, however, significantly lower both in affectively ill (P less than 0.05) and schizophrenic women (P less than 0.001). Postpsychotic fertility in cycloid women was in accordance with expected figures. In affective women it also approximated normality, but in schizophrenic women it was significantly lower than expected. Marital fertility was within the expected interval in cycloid probands. The observations are in support of the opinion that neither prepsychotic nor postpsychotic conditions constitute an unsurmountable obstacle to normal social adaptation in cycloid patients. The differences are also interpreted as an argument in favour of nosological autonomy of the category of cycloid psychosis.

摘要

将1925年首次入院的一组环性精神病患者(n = 34)与同时入院的情感性精神病患者(n = 30)、精神分裂症患者(n = 81)以及该地区的普通人群进行了比较。环性精神病先证者在首次入院时的结婚率与普通人群一致。五年后,该结婚率显著低于预期,但十年后,结婚率在统计学上与预期数字相符。生育率显著高于精神分裂症先证者(P<0.001)。环性精神病女性的生育率与基于女性出生队列平均生育率的预期数字相符。然而,无论是情感性精神病女性(P<0.05)还是精神分裂症女性(P<0.0001),其生育率均显著低于预期。环性精神病女性在精神病发作前的生育率与预期数字无显著差异。然而,情感性精神病女性(P<0.05)和精神分裂症女性(P<0.001)的生育率均显著较低。环性精神病女性在精神病发作后的生育率与预期数字相符。情感性精神病女性的生育率也接近正常水平,但精神分裂症女性的生育率则显著低于预期。环性精神病先证者的婚姻生育率在预期范围内。这些观察结果支持了这样一种观点,即无论是精神病发作前还是发作后的情况,都不会对环性精神病患者的正常社会适应构成不可逾越的障碍。这些差异也被解释为支持环性精神病分类学自主性的一个论据。

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