Hedrick Stephen M
University of California, San Diego, La Jolla, CA 92093-0377, USA.
Immunity. 2008 Mar;28(3):297-9. doi: 10.1016/j.immuni.2008.02.011.
In this issue of Immunity, He et al. (2008) establish the logic and circuitry that determine CD4-CD8 lineage specification. It all comes down to an eighty base pair silencer switch.
在本期《免疫》杂志中,何等人(2008年)确立了决定CD4⁺-CD8⁺谱系分化的逻辑和信号通路。这一切都归结于一个八十碱基对的沉默子开关。