Levang J, Muller P, Marreel A, Nicolas M, Puzenat E, Aubin F, Humbert P
Service de dermatologie, CHU St-Jacques, 25030 Besançon cedex, France.
Ann Dermatol Venereol. 2008 Feb;135(2):111-5. doi: 10.1016/j.annder.2006.06.001. Epub 2008 Feb 1.
Chromomycosis is a widespread subcutaneous fungal infection seen essentially in tropical and subtropical regions and transmitted via skin injury caused by the prickles of plants or infected wood splinters. It is prevalent throughout the West Indies including Guadeloupe, where its incidence is not well known.
This retrospective and descriptive study concerns five histologically established cases of chromomycosis in Guadeloupe between 1995 and 2005. The five patients were diagnosed and treated at Pointe-à-Pitre University Teaching Hospital.
The study concerned four male patients and one female patient with an average age of 78 years; four were from the Basse-Terre district and one was from the Grande-Terre district. The most frequent clinical aspect was nodular or verrucous. The most common initial topography was the upper limbs. Fonsecaea pedrosoi was the only species identified. Diagnosis was confirmed by histopathology, which in all cases revealed sclerotic cells. Three patients underwent surgical treatment and two received medical treatment; only two patients were cured by 2005.
Our study confirms the presence of a source of chromomycosis in Guadeloupe, where Fonsecaea pedrosoi is clearly the best adapted species. It also highlights the difficulties of therapeutic care in tropical areas.
着色芽生菌病是一种广泛存在的皮下真菌感染，主要见于热带和亚热带地区，通过植物刺或受感染的木片造成的皮肤损伤传播。在包括瓜德罗普岛在内的整个西印度群岛都很普遍，但其发病率尚不清楚。
这项回顾性描述性研究涉及1995年至2005年间在瓜德罗普岛经组织学确诊的5例着色芽生菌病病例。这5名患者在皮特尔角大学教学医院被诊断和治疗。
该研究涉及4名男性患者和1名女性患者，平均年龄78岁；4人来自下特雷区，1人来自大特雷区。最常见的临床症状是结节状或疣状。最常见的初始发病部位是上肢。仅鉴定出佩德罗霉。组织病理学确诊，所有病例均显示硬壳细胞。3例患者接受了手术治疗，2例接受了药物治疗；到2005年只有2例患者治愈。
我们的研究证实瓜德罗普岛存在着色芽生菌病传染源，其中佩德罗霉显然是适应性最强的菌种。它还突出了热带地区治疗护理的困难。
