Niaura Raymond
Department of Psychiatry and Human Behavior, Butler Hospital, Providence, Rhode Island 02906, USA.
Am J Med. 2008 Apr;121(4 Suppl 1):S11-9. doi: 10.1016/j.amjmed.2008.01.021.
This article reviews the most common nonpharmacologic approaches used to support smoking cessation and, where possible, provides estimates of their efficacy in controlled clinical trials. Virtually all of the approaches that have been systematically evaluated to date have demonstrated modest efficacy in increasing quit rates. A cornerstone of effective treatment is tobacco dependence counseling, for which there is a dose-response relation between the intensity of counseling (total minutes of contact) and its effectiveness. New approaches in which treatment is tailored to individual patient characteristics appear promising for the future but require further study. Also, new technologies that permit delivery of smoking interventions to a wider range of patients could have a significant impact on reducing smoking prevalence worldwide in the future. Overall, the clinical literature strongly endorses combining nonpharmacologic interventions with pharmacotherapy to optimize support for smokers who are trying to quit.
本文回顾了用于支持戒烟的最常见非药物方法,并在可能的情况下提供了它们在对照临床试验中的疗效估计。几乎所有迄今为止经过系统评估的方法在提高戒烟率方面都显示出适度的疗效。有效治疗的基石是烟草依赖咨询,咨询强度(接触总分钟数)与其有效性之间存在剂量反应关系。根据个体患者特征量身定制治疗的新方法在未来似乎很有前景,但需要进一步研究。此外,能够将吸烟干预措施提供给更广泛患者的新技术可能会对未来全球吸烟率的降低产生重大影响。总体而言,临床文献强烈支持将非药物干预与药物治疗相结合,以优化对试图戒烟的吸烟者的支持。