De-Addiction Centre, National Institute of Mental Health and Neuro Sciences, Bangalore, India.
Curr Opin Psychiatry. 2010 Mar;23(2):151-6. doi: 10.1097/YCO.0b013e328336653f.
Tobacco use causes a significant amount of mortality and morbidity globally. The search for optimal cost-effective treatment interventions continues as current treatment modalities at best offer modest success in treatment outcome. This review evaluates current developments in behavioral interventions for tobacco cessation and their effectiveness.
Most studies of behavioral interventions reported moderate success in quitting tobacco at 6 months. This finding is seen across different professionals providing interventions in diverse settings using various modalities. Behavioral interventions in adolescents and pregnancy seem presently more effective than pharmacotherapy. Technology-driven interventions have gained recent popularity. Combining interventions shows promising results compared with a single intervention.
Most tobacco cessation intervention studies are from developed countries and for cigarette smoking. Long-term cessation still poses a challenge. Given the high global morbidity and mortality, there is a need to develop evidence-based, cost-effective intervention in developing countries for both smoking and smokeless tobacco use. Tobacco addiction produces neurobiological and behavioral change and optimal approaches involving behavioral methods and pharmacotherapy need to be developed.
全球范围内,烟草使用导致了大量的死亡和发病。目前的治疗方法最多只能在治疗效果上取得适度的成功,因此,寻找最佳的具有成本效益的治疗干预措施仍在继续。本综述评估了目前针对烟草戒断的行为干预措施及其效果的最新进展。
大多数行为干预研究报告称,在 6 个月时戒烟的成功率中等。这一发现适用于不同专业人员在不同环境中使用各种方法提供干预措施的情况。在青少年和妊娠期间的行为干预措施目前似乎比药物治疗更有效。基于技术的干预措施最近变得越来越流行。与单一干预措施相比,联合干预措施显示出有前景的结果。
大多数烟草戒断干预研究来自发达国家,针对的是吸烟。长期戒烟仍然是一个挑战。鉴于全球发病率和死亡率高,需要在发展中国家为吸烟和无烟烟草使用制定基于证据、具有成本效益的干预措施。烟草成瘾会导致神经生物学和行为改变,因此需要开发涉及行为方法和药物治疗的最佳方法。