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近视性黄斑劈裂中的光感受器内节和外节缺陷

Photoreceptor inner and outer segment defects in myopic foveoschisis.

作者信息

Sayanagi Kaori, Ikuno Yasushi, Soga Kaori, Tano Yasuo

机构信息

Department of Ophthalmology, Osaka University Medical School, Suita, Osaka, Japan.

出版信息

Am J Ophthalmol. 2008 May;145(5):902-8. doi: 10.1016/j.ajo.2008.01.011. Epub 2008 Mar 14.

Abstract

PURPOSE

To evaluate pathologic features of the photoreceptors in myopic foveoschisis with the Fourier-domain optical coherence tomography (FD-OCT).

DESIGN

Observational case series.

METHODS

Seventeen eyes of 15 patients with myopic foveoschisis (foveal detachment type, six eyes; foveoschisis type, 11 eyes) were included. We observed the photoreceptor inner and outer segments (IS/OS) and evaluated the morphologic status using FD-OCT. Fundus photographs and time-domain OCT (TD-OCT) images also were obtained.

RESULTS

IS/OS defects, which are uncommon in retinal detachments in eyes with myopia, were seen clearly in five eyes (three eyes [50%] with the foveal detachment type; two eyes [18%] with the foveal schisis type). Fundus photographs showed myopic chorioretinal atrophy in eight study eyes (47%), including diffuse atrophy in four eyes (24%) and patchy atrophy in four eyes (24%). The IS/OS defects on FD-OCT were accompanied by myopic chorioretinal atrophy in three (60%) of five eyes.

CONCLUSIONS

FD-OCT enables observation of more detailed retinal structures in these myopic eyes. The IS/OS defects may be specific to, but are not rare, in myopic foveoschisis and may predict the postoperative visual recovery.

摘要

目的

利用傅里叶域光学相干断层扫描(FD - OCT)评估近视性黄斑劈裂中光感受器的病理特征。

设计

观察性病例系列。

方法

纳入15例近视性黄斑劈裂患者的17只眼(黄斑脱离型6只眼;黄斑劈裂型11只眼)。我们观察光感受器内、外节(IS/OS),并使用FD - OCT评估形态学状况。还获取了眼底照片和时域OCT(TD - OCT)图像。

结果

IS/OS缺损在近视眼中的视网膜脱离中并不常见,在5只眼中清晰可见(黄斑脱离型3只眼[50%];黄斑劈裂型2只眼[18%])。眼底照片显示8只研究眼(47%)存在近视性脉络膜视网膜萎缩,包括4只眼(24%)的弥漫性萎缩和4只眼(24%)的斑片状萎缩。5只眼中有3只眼(60%)的FD - OCT上的IS/OS缺损伴有近视性脉络膜视网膜萎缩。

结论

FD - OCT能够观察这些近视眼中更详细的视网膜结构。IS/OS缺损在近视性黄斑劈裂中可能具有特异性,但并不罕见,并且可能预测术后视力恢复。

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