Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Korean J Ophthalmol. 2020 Feb;34(1):67-75. doi: 10.3341/kjo.2019.0115.
To investigate prognostic factors related to the surgical outcome of vitrectomy in myopic traction maculopathy (MTM).
Medical records of patients with MTM who underwent pars plana vitrectomy with internal limiting membrane peeling and follow-up over 12 months were reviewed retrospectively. Best-corrected visual acuity (BCVA), fundoscopic examination and spectral-domain optical coherence tomography findings were evaluated postoperatively. Functional success was defined as visual acuity gain and anatomical success was defined as reduction or resolution of foveoschisis without complications.
This study included 40 eyes of 36 patients. BCVA improved from 0.70 ± 0.44 to 0.63 ± 0.57 logarithm of minimum angle of resolution and central macular thickness decreased from 526.6 ± 132.1 to 277.8 ± 92.1 μm at final follow-up. Functional success was achieved in 24 (60.0%) eyes, and 33 (82.5%) eyes reached anatomical success. Presence of foveal detachment (FD) and higher category of myopic maculopathy were associated with both functional ( = 0.014, 0.021, respectively) and anatomical ( = 0.011, 0.022, respectively) failure. Longer preoperative axial length showed an association with functional failure but not with anatomical failure ( = 0.041). In multivariate analysis, FD was the only prognostic factor for both functional and anatomical outcome ( = 0.041, 0.043, respectively). Preoperative BCVA (r² = 0.259, = 0.001), axial length (r² = 0.172, = 0.008), and myopic maculopathy category (r² = 0.336, < 0.001) showed significant correlation with final BCVA.
More severe myopic maculopathy and the presence of FD are associated with poorer functional and anatomical outcomes of pars plana vitrectomy in MTM. Better preoperative BCVA, shorter axial length, and less severe myopic maculopathy are correlated with better final BCVA.
探讨与近视牵引性黄斑病变(MTM)玻璃体切割术手术结果相关的预后因素。
回顾性分析了 40 只眼 36 例接受经睫状体平坦部玻璃体切割术联合内界膜剥除术并随访 12 个月以上的 MTM 患者的病历。术后评估最佳矫正视力(BCVA)、眼底检查和频域光相干断层扫描(OCT)结果。功能成功定义为视力提高,解剖成功定义为裂孔无并发症并减少或消失。
本研究共纳入 36 例患者的 40 只眼。BCVA 从 0.70±0.44 提高到 0.63±0.57(最小角分辨率对数),中央黄斑厚度从 526.6±132.1 降至 277.8±92.1μm。最终随访时,24 只眼(60.0%)功能成功,33 只眼(82.5%)解剖成功。黄斑裂孔(FD)和更严重的近视性黄斑病变与功能( = 0.014,0.021)和解剖( = 0.011,0.022)失败均相关。较长的术前眼轴与功能失败相关,但与解剖失败无关( = 0.041)。多变量分析显示,FD 是功能和解剖结果的唯一预后因素( = 0.041,0.043)。术前 BCVA(r²=0.259, = 0.001)、眼轴(r²=0.172, = 0.008)和近视性黄斑病变类别(r²=0.336, < 0.001)与最终 BCVA 显著相关。
更严重的近视性黄斑病变和 FD 的存在与 MTM 经睫状体平坦部玻璃体切割术的功能和解剖结果较差相关。更好的术前 BCVA、较短的眼轴和较轻的近视性黄斑病变与更好的最终 BCVA 相关。