Zubkov M N, Shchegolev A G
Zh Mikrobiol Epidemiol Immunobiol. 1976(3):38-42.
Enzymatic properties, sensitivity to antibiotics and peculiarities of the antigenic structure of stable L-forms of S. paratyphi B (L-115), S. typhimurium (L-71a-16) and S. typhi (L-5761) were studied. In difference from the initial strains, the L-form under study possessed a high penicillin and ampicillin sensitivity, and also a marked sensitivity to polymyxin and detergents; this characterized them as L-forms of protoplastic type. All the L-variants differed considerably by the enzymatic properties from the initial strains, and, in the majority of cases, retained the antigenic components and the species-specificity characteristic of the initial parental cultures. Despite the loss of the cell wall the synthesis of O-antigen in the L-forms under study was undisturbed. The 6-forms contained an antigenic component not found in the initial cultures and apparently causing the neutralizing activity of the L-antiser.
对副伤寒杆菌B（L-115）、鼠伤寒沙门氏菌（L-71a-16）和伤寒杆菌（L-5761）稳定L型的酶学特性、对抗生素的敏感性及抗原结构特点进行了研究。与原始菌株不同，所研究的L型对青霉素和氨苄青霉素高度敏感，对多粘菌素和去污剂也有明显敏感性；这表明它们是原生质体型的L型。所有L变体的酶学特性与原始菌株有很大差异，并且在大多数情况下，保留了原始亲代培养物特有的抗原成分和种特异性。尽管细胞壁缺失，但所研究的L型中O抗原的合成未受干扰。这些L型含有原始培养物中未发现的一种抗原成分，显然它导致了L型抗血清的中和活性。
