Aminu M, Ahmad A A, Umoh J U, Dewar J, Esona M D, Steele A D
Faculty of Science, Department of Microbiology, Ahmadu Bello University, Zaria, Nigeria.
J Trop Pediatr. 2008 Oct;54(5):340-2. doi: 10.1093/tropej/fmn021. Epub 2008 Mar 15.
Rotaviruses (RV) are associated with approximately 33 000 deaths in children <5 years of age annually in Nigeria. However, limited data exit on RV infection in north-western Nigeria. During July 2002 to July 2004, 1063 (869 diarrhoeic and 194 control) stool samples were collected from children <5 years of age presenting with diarrhoea in north-western Nigeria. The stools were analysed for RV antigen and further characterized by antigenic and genomic methods. RV was detected in 18% of children with diarrhoea and 7.2% of the age-matched case controls. The highest RV burden was detected in children <6-months-old. Long electropherotypes and VP6 subgroup I + II specificity predominated.
轮状病毒（RV）在尼日利亚每年导致约33000名5岁以下儿童死亡。然而，尼日利亚西北部关于RV感染的数据有限。在2002年7月至2004年7月期间，从尼日利亚西北部5岁以下出现腹泻的儿童中收集了1063份粪便样本（869份腹泻样本和194份对照样本）。对粪便进行RV抗原分析，并通过抗原和基因组方法进一步表征。在18%的腹泻儿童和7.2%年龄匹配的病例对照中检测到RV。在6个月以下的儿童中检测到最高的RV负担。长电泳型和VP6 I + II亚组特异性占主导。
