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在原发性开角型青光眼黄斑评估中,Humphrey视野分析仪、微视野计和海德堡视网膜断层扫描仪的比较。

A comparison among Humphrey field analyzer, Microperimetry, and Heidelberg Retina Tomograph in the evaluation of macula in primary open angle glaucoma.

作者信息

Oztürk Faruk, Yavas Güliz Fatma, Küsbeci Tuncay, Ermis Sitki Samet

机构信息

Faculty of Medicine, Department of Ophthalmology, Afyon Kocatepe University, Afyonkarahisar, Turkey.

出版信息

J Glaucoma. 2008 Mar;17(2):118-21. doi: 10.1097/IJG.0b013e31814b97fd.

Abstract

PURPOSE

It is known that macula can be affected adversely in glaucoma. In this study, we aimed to evaluate the functional and morphologic changes of macula in patients having glaucoma using Microperimeter-1 (MP-1), Humphrey field analyzer (HFA), and Heidelberg Retina Tomograph II (HRT-II).

MATERIALS AND METHODS

This prospective study consisted of 43 patients having primary open angle glaucoma. Control group consisted of 26 normal cases. Macular threshold was evaluated with HFA macula threshold test and MP-1 Humphrey macula pattern. Morphometric evaluation of macula was performed with HRT-II. The results were evaluated by independent samples t test and receiver operator curves.

RESULTS

Macular sensitivity was lower in patients having glaucoma with both HFA and MP-1 in all quadrants (P=0.003 for HFA and P=0.002 for MP-1). The macular thickness measurements obtained with HRT-II was not significant between glaucoma patients and control group (P=0.153). The difference between HFA and MP-1, HFA and HRT-II, MP-1 and HRT-II was not statistically significant (P=0.302, 0.110, and 0.481, respectively).

CONCLUSIONS

Perimetric macular changes can occur while macular topographic remains stable in patients with glaucoma. MP-1 correlates with HFA in detecting glaucomatous visual field defect in macular area.

摘要

目的

已知青光眼可对黄斑产生不良影响。在本研究中,我们旨在使用微视野计-1(MP-1)、汉弗莱视野分析仪(HFA)和海德堡视网膜断层扫描仪II(HRT-II)评估青光眼患者黄斑的功能和形态变化。

材料与方法

这项前瞻性研究纳入了43例原发性开角型青光眼患者。对照组由26例正常受试者组成。使用HFA黄斑阈值测试和MP-1汉弗莱黄斑模式评估黄斑阈值。使用HRT-II对黄斑进行形态学评估。结果通过独立样本t检验和受试者操作曲线进行评估。

结果

青光眼患者在所有象限中,HFA和MP-1测量的黄斑敏感度均较低(HFA为P = 0.003,MP-1为P = 0.002)。青光眼患者和对照组之间,HRT-II测量的黄斑厚度无显著差异(P = 0.153)。HFA与MP-1、HFA与HRT-II、MP-1与HRT-II之间的差异无统计学意义(分别为P = 0.302、0.110和0.481)。

结论

青光眼患者黄斑地形图保持稳定时,视野检查可出现黄斑变化。在检测黄斑区青光眼性视野缺损方面,MP-1与HFA具有相关性。

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