登革热相关性视神经病变
Optic neuropathy associated with dengue fever.
作者信息
Sanjay S, Wagle A M, Au Eong K G
机构信息
Department of Ophthalmology and Visual Sciences, Alexandra Hospital, Singapore, Singapore.
出版信息
Eye (Lond). 2008 May;22(5):722-4. doi: 10.1038/eye.2008.64. Epub 2008 Mar 14.
PURPOSE
To report a case series of three patients of optic neuropathy associated with dengue fever.
METHODS
Observational case series.
RESULTS
Three patients aged of 19, 31, and 40 years (cases 1, 2, and 3) complained of unilateral blurring of vision within a week of being diagnosed with dengue fever. Their presenting visual acuities were counting fingers in cases 1 and 2, and 6/6 in case 3, with features suggestive of optic neuropathy. Two of the three patients (cases 2 and 3) had bilateral ocular signs. The visual acuity recovered to 6/9 in case 1, worsened to no light perception in case 2, and remained unchanged in case 3.
CONCLUSIONS
Although spontaneous visual recovery is possible, optic neuropathy associated with dengue fever may result in severe and permanent visual loss.
目的
报告3例与登革热相关的视神经病变患者的病例系列。
方法
观察性病例系列。
结果
3例患者年龄分别为19岁、31岁和40岁（病例1、2和3），在被诊断为登革热后一周内出现单眼视力模糊。病例1和2的初始视力为眼前指动，病例3为6/6，具有视神经病变的特征。3例患者中有2例（病例2和3）有双侧眼部体征。病例1的视力恢复到6/9，病例2恶化至无光感，病例3保持不变。
结论
虽然视力有可能自发恢复，但与登革热相关的视神经病变可能导致严重且永久性的视力丧失。
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